Innovent Announces First Patient Dosed in a Phase 2 Clinical study of IBI112 (IL-23p19 Monoclonal Antibody) in Patients with Moderate-to-Severe Active Ulcerative Colitis
SAN FRANCISCO and SUZHOU, China , July 4, 2022 |PRNewswire| -- Innovent Biologics, Inc. ("Innovent") (HKEX: 01801), a world-class biopharmaceutical company that develops, manufactures and commercializes high quality medicines for the treatment of cancer, autoimmune, metabolic, ophthalmology and other major diseases, announced that the first patient with moderate-to-severe active ulcerative colitis has been successfully dosed in a Phase 2 clinical study (clinicaltrials.gov, NCT05377580) of its innovative recombinant anti-interleukin 23p19 subunit antibody injection (R D code: IBI112) in China . The study is a multi-center, randomized, double-blind, parallel, placebo-controlled Phase 2 clinical study, evaluating the efficacy and safety of IBI112 in the treatment of moderate-to-severe active ulcerative colitis. The primary objective of the study is to evaluate the efficacy, safety, pharmacokinetics and immunogenicity of IBI112 induction and maintenance therapy in Chinese patients with moderate-to-severe active ulcerative colitis.
Innovent Announces First Patient Dosed in a Phase 2 Clinical study of IBI112 (IL-23p19 Monoclonal Antibody) in Patients with Moderate-to-Severe Active Ulcerative Colitis
SAN FRANCISCO and SUZHOU, China , July 4, 2022 |PRNewswire| -- Innovent Biologics, Inc. ("Innovent") (HKEX: 01801), a world-class biopharmaceutical company that develops, manufactures and commercializes high quality medicines for the treatment of cancer, autoimmune, metabolic, ophthalmology and other major diseases, announced that the first patient with moderate-to-severe active ulcerative colitis has been successfully dosed in a Phase 2 clinical study (clinicaltrials.gov, NCT05377580) of its innovative recombinant anti-interleukin 23p19 subunit antibody injection (R D code: IBI112) in China . The study is a multi-center, randomized, double-blind, parallel, placebo-controlled Phase 2 clinical study, evaluating the efficacy and safety of IBI112 in the treatment of moderate-to-severe active ulcerative colitis. The primary objective of the study is to evaluate the efficacy, safety, pharmacokinetics and immunogenicity of IBI112 induction and maintenance therapy in Chinese patients with moderate-to-severe active ulcerative colitis.