GameStop, Signify Health And Some Other Big Gainers From Monday U.S. stocks closed mixed on Monday. Here is the list of some big stocks moving higher in the previous session. Karuna Therapeutics, Inc. (NASDAQ: KRTX ) shares gained 71.8% to close at $241.19 after the company announced topline results from its Phase 3 EMERGENT-2 trial of KarXT (xanomeline-trospium) in adults with schizophrenia. The trial met its primary endpoint, with KarXT demonstrating a statistically significant and clinically meaningful 9.6-point reduction in the Positive and Negative Syndrome Scale (PANSS) total score compared to placebo. The company also posted a Q2 loss of $2.17 per share. CyberOptics Corporation (NASDAQ: CYBE ) climbed 29% to settle at $53.03 after Nordson said it would acquire the CyberOptics for $54 per share. Professional Holding Corp. (NASDAQ: PFHD ) gained 28% to close at $29.65 after Seacoast announced an agreement to acquire the company in a transaction valued at $488.6 million. Magic Empire Global Limited (NASDAQ: MEGL ) gained 20.6% to close at $117.