55646-99-6 Usage
Description
21-Desacetyl AMcinonide is a derivative of Amcinonide, which is a synthetic glucocorticoid receptor agonist. It is structurally similar to Amcinonide but with a modification in the 21st position of the molecule, where the acetyl group is removed. This modification may result in altered pharmacological properties, such as increased potency, reduced side effects, or improved selectivity for specific glucocorticoid receptor subtypes.
Uses
Used in Pharmaceutical Industry:
21-Desacetyl AMcinonide is used as an anti-inflammatory agent for the treatment of various inflammation and allergic conditions. Its glucocorticoid receptor agonist activity helps to reduce inflammation, suppress the immune system, and alleviate allergic reactions.
Used in Research Applications:
In addition to its therapeutic use, 21-Desacetyl AMcinonide may also be employed as a research tool to study the mechanisms of glucocorticoid receptor signaling and its role in various physiological and pathological processes. This can help in the development of new drugs with improved efficacy and safety profiles for the treatment of inflammation and allergic conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 55646-99-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,6,4 and 6 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 55646-99:
(7*5)+(6*5)+(5*6)+(4*4)+(3*6)+(2*9)+(1*9)=156
156 % 10 = 6
So 55646-99-6 is a valid CAS Registry Number.
55646-99-6Relevant articles and documents
Preparation method of amcinonide
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Paragraph 0021-0026; 0034-0039; 0047-0052; 0060-0065; ..., (2021/11/27)
The invention belongs to the technical field of medicine synthesis, and particularly relates to a preparation method of amcinonide. The method comprises steps: taking a compound I as a raw material, firstly reacting with hydrofluoric acid and cyclopentanone, and then reacting under the action of acetic anhydride and potassium carbonate to obtain the amcinonide. Compared with the prior art, the compound I with lower price is used as a production raw material, so that the cost is reduced, the production amcinonide is easier, the yield is increased, and the amcinonide with better quality is obtained.