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JAMA Network Open Original Investigation Nutrition, Obesity, and Exercise
January 17, 2023
Deirdre K. Tobias, ScD; Heike Luttmann-Gibson, PhD; Samia Mora, MD, MHS; Jacqueline Danik, MD, DrPH; Vadim Bubes, PhD; Trisha Copeland, MS, RD; Meryl S. LeBoff, MD; Nancy R. Cook, ScD; I-Min Lee, MD, ScD; Julie E. Buring, ScD; JoAnn E. Manson, MD, DrPH
open access
JAMA Netw Open. 2023; 6(1):e2250681. 10.1001/jamanetworkopen.2022.50681
This cohort study examines the metabolism of and response to vitamin D supplementation in individuals by levels of vitamin D–related serum biomarkers in association with adiposity.
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JAMA Cardiology Original Investigation
November 23, 2022
Mark A. Hlatky, MD; Pedro Engel Gonzalez, MD; JoAnn E. Manson, MD, DrPH; Julie E. Buring, ScD; I-Min Lee, MBBS, ScD; Nancy R. Cook, ScD; Samia Mora, MD, MHS; Vadim Bubes, PhD; Neil J. Stone, MD
free access
JAMA Cardiol. 2022; 8(1):74-80. 10.1001/jamacardio.2022.4250
This study assesses whether vitamin D supplementation prevents statin-associated muscle symptoms and reduces statin discontinuation.
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JAMA Ophthalmology Original Investigation
June 9, 2022
William G. Christen, ScD; Nancy R. Cook, ScD; JoAnn E. Manson, MD, DrPH; Julie E. Buring, ScD; I-Min Lee, MBBS, ScD; Vadim Bubes, PhD; Georgina Friedenberg, MPH; Rimma Dushkes, PhD; Douglas Smith, BS; Debra A. Schaumberg, ScD, OD, MPH; VITAL Research Group
free access
JAMA Ophthalmol. 2022; 140(7):707-714. 10.1001/jamaophthalmol.2022.1818
This randomized clinical trial evaluates the impact of daily ω-3 supplementation on the development of incident dry eye disease.
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JAMA Original Investigation
December 21, 2021
Olivia I. Okereke, MD, SM; Chirag M. Vyas, MBBS, MPH; David Mischoulon, MD, PhD; Grace Chang, MD, MPH; Nancy R. Cook, ScD; Alison Weinberg, MA; Vadim Bubes, PhD; Trisha Copeland, MS, RD; Georgina Friedenberg, MPH; I-Min Lee, MBBS, ScD; Julie E. Buring, ScD; Charles F. Reynolds III, MD; JoAnn E. Manson, MD, DrPH
free access is active quiz
JAMA. 2021; 326(23):2385-2394. 10.1001/jama.2021.21187
This randomized clinical trial tested the effects of daily omega-3 supplementation vs placebo on depression prevention in older adults without depression.
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JAMA Network Open Original Investigation Oncology
November 18, 2020
Paulette D. Chandler, MD, MPH; Wendy Y. Chen, MD, MPH; Oluremi N. Ajala, MD, MPH; Aditi Hazra, PhD, MPH; Nancy Cook, ScD; Vadim Bubes, PhD; I-Min Lee, MBBS, ScD; Edward L. Giovannucci, MD, ScD; Walter Willett, MD, DrPH; Julie E. Buring, ScD; JoAnn E. Manson, MD, DrPH; VITAL Research Group
open access has multimedia
JAMA Netw Open. 2020; 3(11):e2025850. 10.1001/jamanetworkopen.2020.25850
This secondary analysis of a randomized clinical trial evaluates the effect vitamin D on the incidence of advanced (metastatic or fatal) cancer among adults without cancer at baseline and examines possible effect modification by body mass index.
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JAMA Ophthalmology Original Investigation
October 29, 2020
William G. Christen, ScD; Nancy R. Cook, ScD; JoAnn E. Manson, MD, DrPH; Julie E. Buring, ScD; Daniel I. Chasman, PhD; I-Min Lee, MBBS, ScD; Vadim Bubes, PhD; Chunying Li, PhD; Margarette Haubourg; Debra A. Schaumberg, ScD; VITAL Research Group
free access
JAMA Ophthalmol. 2020; 138(12):1280-1289. 10.1001/jamaophthalmol.2020.4409
This prespecified ancillary analysis of the VITAL (Vitamin D and Omega-3 Trial) nationwide randomized clinical trial assesses whether daily supplementation for approximately 4 to 6 years with vitamin D3, marine ω-3 fatty acids, or both vs placebo prevents the development or progression of age-related macular degeneration in initially healthy US adults.
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JAMA Original Investigation
August 4, 2020
Olivia I. Okereke, MD, SM; Charles F. Reynolds III, MD; David Mischoulon, MD, PhD; Grace Chang, MD, MPH; Chirag M. Vyas, MBBS, MPH; Nancy R. Cook, ScD; Alison Weinberg, MA; Vadim Bubes, PhD; Trisha Copeland, MS, RD; Georgina Friedenberg, MPH; I-Min Lee, MBBS, ScD; Julie E. Buring, ScD; JoAnn E. Manson, MD, DrPH
free access
JAMA. 2020; 324(5):471-480. 10.1001/jama.2020.10224
This randomized clinical trial compares the effects of vitamin D₃ supplementation vs placebo on depression risk and mood scores in men and women aged 50 years or older.
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JAMA Original Investigation
June 9, 2020
Tobias Kurth, MD, ScD; Pamela M. Rist, ScD; Paul M Ridker, MD, MPH; Gregory Kotler, PhD; Vadim Bubes, PhD; Julie E. Buring, ScD
free access
JAMA. 2020; 323(22):2281-2289. 10.1001/jama.2020.7172
This cohort study uses Women’s Health Study data to compare the association of migraine with aura vs other major vascular risk factors (diabetes, hypertension, dyslipidemia, smoking, BMI, CVD family history) with incidence of cardiovascular disease.
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JAMA Cardiology Original Investigation
June 1, 2017
Susanne Rautiainen, PhD; J. Michael Gaziano, MD, MPH; William G. Christen, ScD; Vadim Bubes, PhD; Gregory Kotler, PhD; Robert J. Glynn, ScD; JoAnn E. Manson, MD, DrPH; Julie E. Buring, ScD; Howard D. Sesso, ScD, MPH
free access
JAMA Cardiol. 2017; 2(6):617-625. 10.1001/jamacardio.2017.0176
This secondary analysis of the Physicians’ Health Study II randomized clinical trial investigates effect modification by various baseline dietary factors on cardiovascular disease risk.
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JAMA Original Contribution ONLINE FIRST
November 14, 2012
J. Michael Gaziano, MD, MPH; Howard D. Sesso, ScD, MPH; William G. Christen, ScD; Vadim Bubes, PhD; Joanne P. Smith, BA; Jean MacFadyen, BA; Miriam Schvartz, MD; JoAnn E. Manson, MD, DrPH; Robert J. Glynn, ScD; Julie E. Buring, ScD
free access
JAMA. 2012; 308(18):1871-1880. 10.1001/jama.2012.14641
To determine whether long-term multivitamin supplementation decreases the risk of total and site-specific cancer events among men, Gaziano and coauthors tested a multivitamin regimen on 14 641 US male physicians. See related Editorial by Bach and Lewis.
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JAMA Original Contribution
November 7, 2012
Howard D. Sesso, ScD, MPH; William G. Christen, ScD; Vadim Bubes, PhD; Joanne P. Smith, BA; Jean MacFadyen, BA; Miriam Schvartz, MD; JoAnn E. Manson, MD, DrPH; Robert J. Glynn, ScD; Julie E. Buring, ScD; J. Michael Gaziano, MD, MPH
free access has multimedia
JAMA. 2012; 308(17):1751-1760. 10.1001/jama.2012.14805
To determine whether long-term multivitamin supplementation decreases the risk of major cardiovascular events among men, Sesso and coauthors randomized 14 641 male physicians participating in the Physicians’ Health Study II to receive a multivitamin or placebo. Lonn provides comment in the related Editorial.
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JAMA Original Investigation
November 8, 2019
Ian H. de Boer, MD, MS; Leila R. Zelnick, PhD; John Ruzinski, BS; Georgina Friedenberg, MPH; Julie Duszlak, BS; Vadim Y. Bubes, PhD; Andrew N. Hoofnagle, MD, PhD; Ravi Thadhani, MD, MPH; Robert J. Glynn, PhD, ScD; Julie E. Buring, ScD; Howard D. Sesso, ScD, MPH; JoAnn E. Manson, MD, DrPH
free access
JAMA. 2019; 322(19):1899-1909. 10.1001/jama.2019.17380
This 2 × 2 factorial trial compares the effects of vitamin D3 vs placebo and omega-3 fatty acids vs placebo on change in glomerular filtration rate estimated from serum creatinine and cystatin C (eGFR) over 5 years in adults with type 2 diabetes.
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JAMA Ophthalmology Clinical Trials
November 8, 2010
William G. Christen, ScD; Robert J. Glynn, ScD; Howard D. Sesso, ScD; Tobias Kurth, MD; Jean MacFadyen, BA; Vadim Bubes, PhD; Julie E. Buring, ScD; JoAnn E. Manson, MD; J. Michael Gaziano, MD
Arch Ophthalmol. 2010; 128(11):1397-1405. 10.1001/archophthalmol.2010.266
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JAMA Original Contribution
January 7, 2009
J. Michael Gaziano, MD, MPH; Robert J. Glynn, ScD; William G. Christen, ScD; Tobias Kurth, MD, ScD; Charlene Belanger, MA; Jean MacFadyen, BA; Vadim Bubes, PhD; JoAnn E. Manson, MD, DrPH; Howard D. Sesso, ScD, MPH; Julie E. Buring, ScD
free access
JAMA. 2009; 301(1):52-62. 10.1001/jama.2008.862
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JAMA Original Contribution
November 12, 2008
Howard D. Sesso, ScD, MPH; Julie E. Buring, ScD; William G. Christen, ScD; Tobias Kurth, MD, ScD; Charlene Belanger, MA; Jean MacFadyen, BA; Vadim Bubes, PhD; JoAnn E. Manson, MD, DrPH; Robert J. Glynn, ScD; J. Michael Gaziano, MD, MPH
free access
JAMA. 2008; 300(18):2123-2133. 10.1001/jama.2008.600
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JAMA Internal Medicine Editor's Correspondence
November 12, 2007
Tobias Kurth, MD, ScD; J. Michael Gaziano, MD, MPH; Nancy R. Cook, ScD; Vadim Bubes, PhD; Giancarlo Logroscino, MD, PhD; Hans-Christoph Diener, MD, PhD; Julie E. Buring, ScD
Arch Intern Med. 2007; 167(20):2264-2265. 10.1001/archinte.167.20.2264-b
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JAMA Internal Medicine Original Investigation
April 23, 2007
Tobias Kurth, MD, ScD; J. Michael Gaziano, MD, MPH; Nancy R. Cook, ScD; Vadim Bubes, PhD; Giancarlo Logroscino, MD, PhD; Hans-Christoph Diener, MD, PhD; Julie E. Buring, ScD
free access
Arch Intern Med. 2007; 167(8):795-801. 10.1001/archinte.167.8.795