P-value color scale
> 10-3 10-3 to 10-5 10-5 to 10-7 10-7 to 10-9 < 10-9

 

GO term Description P-value FDR q-value Enrichment (N, B, n, b) Genes
GO:2000045 regulation of G1/S transition of mitotic cell cycle 9.13E-5 8.51E-1 2.06 (4735,78,795,27) [+] Show genes
GO:0033238 regulation of cellular amine metabolic process 1.05E-4 4.91E-1 2.34 (4735,51,795,20) [+] Show genes
GO:1902807 negative regulation of cell cycle G1/S phase transition 1.21E-4 3.76E-1 2.13 (4735,67,795,24) [+] Show genes
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 1.21E-4 2.82E-1 2.13 (4735,67,795,24) [+] Show genes
GO:1902806 regulation of cell cycle G1/S phase transition 1.89E-4 3.52E-1 1.99 (4735,81,795,27) [+] Show genes
GO:0002376 immune system process 2.17E-4 3.37E-1 1.32 (4735,583,795,129) [+] Show genes
GO:0071158 positive regulation of cell cycle arrest 2.68E-4 3.58E-1 2.16 (4735,58,795,21) [+] Show genes
GO:0030330 DNA damage response, signal transduction by p53 class mediator 3.5E-4 4.08E-1 2.08 (4735,63,795,22) [+] Show genes
GO:0048771 tissue remodeling 3.56E-4 3.68E-1 3.67 (4735,13,795,8) [+] Show genes
GO:0045787 positive regulation of cell cycle 4.08E-4 3.8E-1 1.73 (4735,124,795,36) [+] Show genes
GO:0006521 regulation of cellular amino acid metabolic process 4.45E-4 3.77E-1 2.23 (4735,48,795,18) [+] Show genes
GO:0071156 regulation of cell cycle arrest 4.51E-4 3.5E-1 2.05 (4735,64,795,22) [+] Show genes
GO:0015711 organic anion transport 5.1E-4 3.65E-1 1.93 (4735,77,795,25) [+] Show genes
GO:0051352 negative regulation of ligase activity 6E-4 4E-1 2.09 (4735,57,795,20) [+] Show genes
GO:0051444 negative regulation of ubiquitin-protein transferase activity 6E-4 3.73E-1 2.09 (4735,57,795,20) [+] Show genes
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 6.02E-4 3.51E-1 2.14 (4735,53,795,19) [+] Show genes
GO:0010499 proteasomal ubiquitin-independent protein catabolic process 6.84E-4 3.75E-1 3.15 (4735,17,795,9) [+] Show genes
GO:0006094 gluconeogenesis 7.08E-4 3.67E-1 3.40 (4735,14,795,8) [+] Show genes
GO:0051438 regulation of ubiquitin-protein transferase activity 7.3E-4 3.58E-1 1.99 (4735,66,795,22) [+] Show genes
GO:1902400 intracellular signal transduction involved in G1 DNA damage checkpoint 7.86E-4 3.66E-1 2.10 (4735,54,795,19) [+] Show genes
GO:1902403 signal transduction involved in mitotic DNA integrity checkpoint 7.86E-4 3.49E-1 2.10 (4735,54,795,19) [+] Show genes
GO:1902402 signal transduction involved in mitotic DNA damage checkpoint 7.86E-4 3.33E-1 2.10 (4735,54,795,19) [+] Show genes
GO:0072431 signal transduction involved in mitotic G1 DNA damage checkpoint 7.86E-4 3.19E-1 2.10 (4735,54,795,19) [+] Show genes
GO:0072413 signal transduction involved in mitotic cell cycle checkpoint 7.86E-4 3.05E-1 2.10 (4735,54,795,19) [+] Show genes
GO:0044093 positive regulation of molecular function 9.14E-4 3.41E-1 1.32 (4735,480,795,106) [+] Show genes
GO:0006811 ion transport 9.99E-4 3.58E-1 1.41 (4735,295,795,70) [+] Show genes

Species used: Homo sapiens

The system has recognized 6159 genes out of 6159 gene terms entered by the user.
6159 genes were recognized by gene symbol and 0 genes by other gene IDs .
881 duplicate genes were removed (keeping the highest ranking instance of each gene) leaving a total of 5278 genes.
Only 4735 of these genes are associated with a GO term.

The GOrilla database is periodically updated using the GO database and other sources.
The GOrilla database was last updated on May 30, 2015

This results page will be available on this site for one month from now (until Jul 5, 2015 ). You can bookmark this page and come back to it later.


'P-value' is the enrichment p-value computed according to the mHG or HG model. This p-value is not corrected for multiple testing of 9324 GO terms.

'FDR q-value' is the correction of the above p-value for multiple testing using the Benjamini and Hochberg (1995) method.
Namely, for the ith term (ranked according to p-value) the FDR q-value is (p-value * number of GO terms) / i.

Enrichment (N, B, n, b) is defined as follows:
N - is the total number of genes
B - is the total number of genes associated with a specific GO term
n - is the number of genes in the top of the user's input list or in the target set when appropriate
b - is the number of genes in the intersection
Enrichment = (b/n) / (B/N)

Genes: For each GO term you can see the list of associated genes that appear in the optimal top of the list.
Each gene name is specified by gene symbol followed by a short description of the gene

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