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Interferon-Like Virus-Inhibitor Induced in Human Leukocytes by Phytohemagglutinin

E. Frederick WheelockAuthors Info & Affiliations
Science
16 Jul 1965
Vol 149, Issue 3681
pp. 310-311
DOI: 10.1126/science.149.3681.310
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Abstract

Phytohemagglutinin, an extract of the kidney bean, Phaseolus vulgaris, induces in human leukocyte cultures an inhibitor of the cytopathic effects of Sindbis virus. The physicochemical and biological properties of this virus-inhibitor are similar to those of interferon induced by Newcastle disease virus, except for an instability at pH 2 and 10 and at 56°C.

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Published In

Science
Volume 149 | Issue 3681
16 July 1965

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1965 by the American Association for the Advancement of Science.

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Published in print: 16 July 1965

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E. Frederick Wheelock
Departments of Preventive Medicinev and Medicine, School of Medicine, Western Reserve University, and University Hospitals, Cleveland, Ohio
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  • E. Frederick Wheelock
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Interferon-Like Virus-Inhibitor Induced in Human Leukocytes by Phytohemagglutinin.Science149,310-311(1965).DOI:10.1126/science.149.3681.310

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