A Stochastic Multi-Strain SIR Model with Two-Dose Vaccination Rate
Abstract
:1. Introduction
2. The Model
2.1. The Equilibrium Point and the Basic Reproduction Number
2.2. Sensitivity Analysis of the Basic Reproduction Number to Parameters
2.3. The Stochastic Model
3. The Asymptotic Behavior of the Stochastic Model
3.1. Existence of Unique Positive Solution
3.2. Extinction
- (a)
-
and , or
- (b)
-
.
- (a)
-
and , or
- (b)
-
,
3.3. Persistence
- (a)
-
If , we have
- (b)
-
If there are some persistent strains with and , then
- (a)
-
and , or
- (b)
-
and ,
3.4. Vaccination Rates
4. Numerical Examples
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Appendix A
Appendix B
- (a)
-
Using model (12) and Equation (16), we have
- (b)
-
If , by Equation (A16),
Appendix C
- (a)
-
Using (A12) and (A16),
- (b)
-
Using (A12) and (A17),
Appendix D
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Variable/Parameter | Description |
---|---|
the birth rate | |
the rate at which immunity disappears in recovered individuals | |
the vaccination rate of the first dose among susceptible individuals | |
the vaccination rate of the second dose among individuals who received first dose of vaccine | |
the rate at which immunity disappears among susceptible individuals receiving 1 dose of vaccine | |
the rate at which immunity disappears among susceptible individuals receiving 2 doses of vaccine | |
the natural death rate |
Parameter | PRCC | Parameter | PRCC |
---|---|---|---|
0.8258 ** | −0.1198 ** | ||
0.3185 ** | −0.1515 ** | ||
0.2817 ** | −0.2133 ** | ||
0.2523 ** | −0.1224 ** | ||
−0.0699 * | −0.0917 ** | ||
0.0530 | −0.8421 ** | ||
0.1044 ** | −0.3632 ** | ||
−0.1843 ** | −0.0481 |
(0.1, 0.1) | 8.6662 | 5.7327 |
(0.1, 0.5) | 8.1300 | 5.6695 |
(0.1, 0.9) | 7.9410 | 5.6458 |
(0.5, 0.1) | 4.5833 | 4.9769 |
(0.5, 0.5) | 3.9022 | 4.7210 |
(0.5, 0.9) | 3.6912 | 4.6240 |
(0.9, 0.1) | 3.1151 | 4.2961 |
(0.9, 0.5) | 2.5669 | 3.8537 |
(0.9, 0.9) | 2.4041 | 3.6848 |
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Chang, Y.-C.; Liu, C.-T. A Stochastic Multi-Strain SIR Model with Two-Dose Vaccination Rate. Mathematics 2022, 10, 1804. https://doi.org/10.3390/math10111804
Chang Y-C, Liu C-T. A Stochastic Multi-Strain SIR Model with Two-Dose Vaccination Rate. Mathematics. 2022; 10(11):1804. https://doi.org/10.3390/math10111804
Chicago/Turabian StyleChang, Yen-Chang, and Ching-Ti Liu. 2022. "A Stochastic Multi-Strain SIR Model with Two-Dose Vaccination Rate" Mathematics 10, no. 11: 1804. https://doi.org/10.3390/math10111804