Prevalence and Incidence Studies of Mood Disorders: A Systematic Review of the Literature
Abstract
Abstract
This is the second in a series of papers that present systematic reviews of the prevalence and incidence of psychiatric disorders drawn from studies published in English literature in the years 1980 to 2000. The series discusses the implications of these epidemiologic findings to mental health policy and practice.
Objective:
To present the results of a systematic review of literature published between January 1, 1980, and December 31, 2000, that reports findings on the prevalence and incidence of mood disorders in both general population and primary care settings.
Method:
We conducted a literature search of epidemiologic studies of mood disorders, using Medline and HealthSTAR databases and canvassing English-language publications. Eligible publications were restricted to studies that examined subjects aged at least 15 years and over. We used a set of predetermined inclusion and exclusion criteria to identify relevant studies. We extracted and analyzed prevalence and incidence data for heterogeneity.
Results:
Of general population studies, a total of 18 prevalence and 5 incidence studies met eligibility criteria. We found heterogeneity across 1-year and lifetime prevalence of major depressive disorder (MDD), dysthymic disorder, and bipolar I disorder. The corresponding pooled rates for 1-year prevalence were 4.1 per 100, 2.0 per 100, and 0.72 per 100, respectively. For lifetime prevalence, the corresponding pooled rates were 6.7 per 100, 3.6 per 100, and 0.8 per 100, respectively. Significant variation was observed among 1-year incidence rates of MDD, with a corresponding pooled rate of 2.9 per 100.
Conclusions:
The prevalence of mood disorders reported in high-quality studies is generally lower than rates commonly reported in the general psychiatric literature. When controlled for common methodological confounds, variation in prevalence rates persists across studies and deserves continued study. Methodological variation among studies that have examined the prevalence of depression in primary health care services is so large that comparative analyses cannot be achieved.
Résumé
Objectif:
Présenter les résultats d'un examen méthodique de la documentation publiée entre le 1er janvier 1980 et le 31 décembre 2000 qui comporte des résultats sur la prévalence et l'incidence des troubles de l'humeur dans la population générale et dans les établissements de soins primaires.
Méthode:
Nous avons mené une recherche dans la documentation sur les études épidémiologiques des troubles de l'humeur, à l'aide des bases de données Medline et HealthSTAR, et avons parcouru les publications en anglais. N'étaient admissibles que les publications limitées aux études qui examinaient des sujets âgés d'au moins 15 ans et plus. Nous avons utilisé un ensemble de critères prédéterminés d'inclusion et d'exclusion pour déterminer les études pertinentes. Nous avons extrait les données de prévalence et d'incidence, et en avons analysé l'hétérogénéité.
Résultats:
Parmi les études sur la population générale, un total de 18 études de prévalence et de 5 études d'incidence satisfaisaient aux critères d'admissibilité. L'hétérogénéité a été constatée dans toute la prévalence d'un an et de durée de vie du trouble dépressif majeur, du trouble dysthymique et du trouble bipolaire. Les taux pondérés correspondants pour la prévalence d'un an étaient 4,1%, 2,0% et 0,72%, respectivement. En ce qui concerne la prévalence de durée de vie, les taux pondérés correspondants étaient 6,7%, 3,6% et 0,8%, respectivement. Une variation importante a été observée parmi les taux d'incidence d'un an du trouble dépressif majeur, avec un taux pondéré correspondant de 2,9%.
Conclusions:
La prévalence des troubles de l'humeur constatée dans les études de qualité supérieure est généralement plus faible que les taux fréquemment déclarés dans la documentation psychiatrique générale. Lors du contrôle des confusions méthodologiques communes, la variation des taux de prévalence persiste parmi les études et mérite une recherche continue. La variation méthodologique entre les études qui examinaient la prévalence de la dépression dans les services de soins primaires était si importante qu'on ne peut mener d'analyses comparatives.
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Depressive Disorders
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Understanding the pathophysiology of depression: From monoamines to th...
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Gender differences in subtypes of depression by first incidence and ag...
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Effects of mindfulness exercises as stand-alone intervention on sympto...
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Efficacy and moderators of psychological interventions in treating sub...
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Correlation between allopregnanolone levels and depressive symptoms du...
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Is the Higher Number of Suicide Attempts in Bipolar Disorder vs. Major...
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Unipolar Depression
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Scenes Design in Virtual Reality for Depression Assessment
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Chronobiology and Treatment in Depression
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Prevalence of depression and anxiety in rheumatoid arthritis patients ...
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Insomnia and hypersomnia in major depressive episode: Prevalence, soci...
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Head and Neck Cancer Survivorship: Learning the Needs, Meeting the Nee...
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Combined serum levels of multiple proteins in tPA-BDNF pathway may aid...
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Factors Associated With Global Variability in Electroconvulsive Therap...
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Serum albumin levels and depression in people living with Human Immuno...
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Human papillomavirus tumour status is not associated with a positive d...
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Patients’ Perspectives on the Psychological Impact of Inflammatory Art...
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The prevalence of depression in rheumatoid arthritis in China: A syste...
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The relationship between chronotype and depressive symptoms: A meta-an...
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Under-diagnosis of mood disorders in Canada
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Effect of blue-blocking glasses in major depressive disorder with slee...
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Interaction of Depression and Anxiety in the Development of Mixed Anxi...
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Utility scores for different health states related to depression: indi...
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Sudarshan Kriya Yoga improves cardiac autonomic control in patients wi...
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Hospitalization and other risk factors for depressive and anxious symp...
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Use of benzodiazepine and risk of cancer: A meta-analysis of observati...
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The correlations of socioeconomic status, disease activity, quality of...
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Psychological interventions for post-traumatic stress disorder (PTSD) ...
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Rheumatoid Arthritis
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Depression in Chronic Kidney Disease and End-Stage Renal Disease: Simi...
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Psychedelics in the treatment of unipolar mood disorders: a systematic...
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Are depression and anxiety associated with disease activity in rheumat...
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Effect of psychotherapy for depression on quality of life: meta-analys...
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The Prevalence of Electroconvulsive Therapy Use Since 1973
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Incentives and disincentives for treating of depression and anxiety in...
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Psychodermatology and Psychocutaneous Disease
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Association between compliance with physical activity guidelines, sede...
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Does Internet-based guided-self-help for depression cause harm? An ind...
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Supportive Care: Integration of Patient-Centered Kidney Care to Manage...
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Syndrome dépressif et absentéisme chez le personnel soignant de la rég...
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Accounting for Depressive Realism in Contingency Judgments: Attentiona...
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Perceived Discrimination, Acculturation, Acculturative Stress, and Dep...
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Influence of religion and supernatural beliefs on clinical manifestati...
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The Influence of Pain, Weakness and Rheumatoid Factor Status on Depres...
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Economic evaluation of Internet-based problem-solving guided self-help...
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Do people with bipolar disorders have access to psychosocial treatment...
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High Rates of Undiagnosed Psychological Distress Exist in a Referral P...
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Management of bipolar disorder in the intercontinental region: an inte...
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Mindfulness-Based Stress Reduction for Posttraumatic Stress Disorder, ...
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Pathogenetic and Therapeutic Applications of Tumor Necrosis Factor-α (...
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Depression as a Risk Factor for the Initial Presentation of Twelve Car...
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How Mental Health Is Shortchanged by Lack of Reimbursement for Vagus N...
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Depression requiring anti-depressant drug therapy in adult congenital ...
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References
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Exercise for the treatment of depression
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Is serum 25-hydroxyvitamin D associated with depressive symptoms and s...
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Unipolar Depression
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Differentiation between major depressive disorder and bipolar disorder...
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Influence of Tryptophan and Serotonin on Mood and Cognition with a Pos...
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The development and psychometric properties of a measure of clinicians...
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The serotonin transporter in depression: Meta-analysis of in vivo and ...
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Factors Associated with the Use of Complementary and Alternative Medic...
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Environmental manipulation affects depressive-like behaviours in femal...
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Prevalence and sociodemographic correlates of depressive and bipolar d...
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Managing inadequate antidepressant response in depressive illness
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Environmental and individual characteristics associated with depressiv...
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Prevalence of Depression in Patients With Hypertension
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Prevalence of major depressive disorder and socio-demographic correlat...
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Social phobia and quality of life in morbidly obese patients before an...
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Changes in rates of recorded depression in English primary care 2003–2...
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Behavioural and cognitive-behavioural therapy based self-help versus t...
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Antidepressant therapy in cancer patients: initiation and factors asso...
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Bipolar disorder prevalence: a systematic review and meta-analysis of ...
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Evidence-based guidelines for treating depressive disorders with antid...
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Mood and Anxiety Disorders in Chronic Fatigue Syndrome, Fibromyalgia, ...
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Psychoeducation for siblings of people with severe mental illness
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The influence of comorbid chronic physical conditions on depression re...
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Prevalence of Bipolar I and II Disorder in Canada
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The Association Between Diagnosis, Treatment Delay and Outcome Among P...
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Diagnosis of bipolar disorder in primary and secondary care: What have...
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Do patients׳ illness beliefs predict depression measures at six months...
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Psychological interventions for post-traumatic stress disorder (PTSD) ...
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Performance of Screening Tools in Detecting Major Depressive Disorder ...
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Evaluating the efficacy and cost-effectiveness of web-based indicated ...
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Early specific cognitive-behavioural psychotherapy in subjects at high...
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GET.ON Mood Enhancer: efficacy of Internet-based guided self-help comp...
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Symptoms mimicking dementia in a 60-year-old woman with bipolar disord...
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C-reactive protein and depression in persons with Human Immunodeficien...
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Frequency vs. intensity: Framing effects on patients' use of verbal ra...
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Prevalence, associations, and adequacy of treatment of major depressio...
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Relationship between the prefrontal function and the severity of the e...
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Prevalence of depression morbidity among Brazilian adults: a systemati...
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Predictors of Incident Depression in Systemic Lupus Erythematosus
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The Longitudinal Prediction of Costs due to Health Care Uptake and Pro...
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Non-Synonymous Single Nucleotide Polymorphisms in the P2X Receptor Gen...
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Comparison of agomelatine and selective serotonin reuptake inhibitors/...
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Enduring effects of evidence-based psychotherapies in acute depression...
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Folate Augmentation of Treatment – Evaluation for Depression (FolATED)...
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Determinants of quality of life in advanced kidney disease: time to sc...
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Electromyographic analysis of masseter and temporal muscles, bite forc...
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Under-reporting bipolar disorder in large-scale epidemiologic studies
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The projected effect of risk factor reduction on major depression inci...
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The global prevalence of common mental disorders: a systematic review ...
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Biological vulnerability to depression: linked structural and function...
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Genetic variant of AKT1 and ...
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Perceived Family Support, Depression, and Suicidal Ideation among Peop...
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Peripheral tumors alter neuroinflammatory responses to lipopolysacchar...
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Bone-targeted therapy for metastatic breast cancer—Where do we go from...
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Prevalence of Gastroesophageal Reflux Disease in Major Depressive Diso...
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Psychosocial factors associated with impact of cancer in longterm haem...
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BDNF Met66 modulates the cumulative effect of psychosoci...
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Depression, suicide, and violence
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Review of psychotherapeutic interventions on depression in cancer pati...
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Prevalence of depression in cancer patients: a meta‐analysis of diagno...
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Combination Psychotherapy and Antidepressant Medication Treatment for ...
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Classification, Causes, and Epidemiology
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Food can lift mood by affecting mood-regulating neurocircuits via a se...
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Workplace risk factors for anxiety and depression in male-dominated in...
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Low-dose oral isotretinoin versus topical retinoic acid for photoaging...
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Short-Term Effects of a Web-Based Guided Self-Help Intervention for Em...
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Long-Term Results of a Web-Based Guided Self-Help Intervention for Emp...
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Implementation Strategies for Improving the Care of Depressed Elderly ...
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Aripiprazole alone or in combination for acute mania
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The prevalence of depression in rheumatoid arthritis: a systematic rev...
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Internet-based treatment of major depression for patients on a waiting...
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Web-based guided self-help for employees with depressive symptoms (Hap...
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Implementing a knowledge application program for anxiety and depressio...
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Bibliographie
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Detecting Depression in Patients with Coronary Heart Disease: a Diagno...
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The epidemiological modelling of dysthymia: Application for the Global...
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REM sleep dysregulation in depression: State of the art
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Sensitivity and specificity of clinician administered screening instru...
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From the stressed adolescent to the anxious and depressed adult: Inves...
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Borrosidades patológicas
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Prevalence and predictors of pain in patients with major depressive di...
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Retinoids for prevention and treatment of actinic keratosis
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Depression and anxiety in long-term cancer survivors compared with spo...
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Insulin-like growth factor 1 (IGF-1) expression is up-regulated in lym...
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Prevalence of depression in chronic kidney disease: systematic review ...
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World Federation of Societies of Biological Psychiatry (WFSBP) Guideli...
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Psychoeducation for siblings of people with severe mental illness
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Health status assessment tool for the family member caregiver of patie...
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Higher prevalence of major depressive symptoms in Brazilians aged 14 a...
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Psychotrichology: psychosomatic aspects of hair diseases
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Using Anonymized, Routinely Collected Health Data in Wales to Estimate...
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Systematic review of the prevalence of bipolar disorder and bipolar sp...
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The Development and First Use of the QUEST Measures to Evaluate School...
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A fuzzy cognitive map of the psychosocial determinants of obesity
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Incidence, patient characteristics and treatment initiated for GP-diag...
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Quetiapine monotherapy in acute phase for major depressive disorder: a...
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Comparing the accuracy of brief versus long depression screening instr...
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A pilot randomised controlled trial of personalised care for depressed...
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Difference between the prevalence of symptoms of depression and anxiet...
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Increased ratio of anti-apoptotic to pro-apoptotic Bcl2 gene-family me...
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Comorbidity in Perimenstrual Migraine
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Transcranial direct current stimulation for the treatment of major dep...
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Women's Health Psychology
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The Prevalence of Depression in Pediatric Oncology Patients Undergoing...
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A moderate-sodium DASH-type diet improves mood in postmenopausal women
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Metyrapone in treatment-resistant depression
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Symptoms of Posttraumatic Stress Disorder Among Pediatric Acute Care N...
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The Burden of Mental Disorders
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Symptoms and treatment of bipolar patients in Sweden
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Frontal and right temporal activations correlate negatively with depre...
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Depression and Dysthymic Disorders
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Differential Impact of Risk Factors for Women and Men on the Risk of M...
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Methodology and reporting of systematic reviews and ...
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Does anxiety increase impulsivity in patients with bipolar disorder or...
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Beliefs about causes, behavioural manifestations and treatment of bord...
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Evidence-Based Treatment of Depression in Patients With Cancer
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Patterns of Alcohol and Other Drug Use Associated with Major Depressio...
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Predictors of relapse or recurrence in bipolar I disorder
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Depressive disorders and the menopause transition
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Unipolar depressive Störungen
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Increasing prevalence of depression from 2000 to 2006
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Early Detection and Intervention in Bipolar Affective Disorder: Target...
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Typology of adults diagnosed with mental disorders based on socio-demo...
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Prevalence and psychopathological characteristics of depression in con...
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PHQ-8 Days: a measurement option for DSM-5 Major Depressive Disorder (...
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A systematic review of the global distribution and availability of pre...
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Tasas de prevalencia de depresión en atención primaria en relación con...
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Depression
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Outcome of depression in primary care: Better than expected
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Association Between Tryptophan Hydroxylase-2 Gene and Late-Onset Depre...
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A follow‐up case–control association study of tractable (druggable) ge...
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Prevention of depressive disorders: towards a further reduction of the...
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Understanding the use of antidepressants
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Sex‐Related Differences in Epidemiological and Clinic‐Based Headache S...
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Epidemiology of Bipolar Disorder in Adults and Children
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Berücksichtigung biopsychosozialer Aspekte vor kosmetischen Operatione...
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Childhood Parental Loss and Bipolar Spectrum in Obese Bariatric Surger...
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Prevalence of depression, anxiety, and adjustment disorder in oncologi...
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International comparison of clinicians' ability to identify depression...
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Classification, causes, and epidemiology
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Poverty, life events and the risk for depression in Uganda
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Vitamin status and psychiatric disorders
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The Patient Health Questionnaire-9 for detection of major depressive d...
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The emerging modern face of mood disorders: a didactic editorial with ...
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Increased peripheral blood expression of electron transport chain gene...
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Ziprasidone alone or in combination for acute mania
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Work impairment in bipolar disorder patients – results from a two-year...
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Update on the Epidemiology of Bipolar Disorder
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A population-based analysis of distinguishers of bipolar disorder from...
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▼Agomelatine for major depressive episodes
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The Prevalence of Mood and Anxiety Disorders in Australian Women
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Genome-wide association study of recurrent major depressive disorder i...
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Neuromodulation approaches for the treatment of major depression: chal...
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The Social Epidemiology of Mental Disorder
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Assessing mixed anxiety-depressive disorder. A national primary care s...
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Psychocutaneous Disorders
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Investigations of HPA function and the enduring consequences of stress...
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A Comparison of Desipramine Response in Younger and Older Women
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Therapeutic Options for Treatment-Resistant Depression
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Incidence of Psychotic Disorders in the 50 Year Follow Up of the Lundb...
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The Societal Costs of Anxiety and Mood Disorders: An Epidemiological P...
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Special Issue on Computerized Treatments of Depression
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Accumulation of major depressive episodes over time in a prospective s...
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The effect of major depression on participation in preventive health c...
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Recent trends in the incidence of recorded depression in primary care
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Recurrence Rates in Ontario Physicians Monitored for Major Depression ...
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A 3‐week, randomized, placebo‐controlled trial of asenapine in the tre...
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Remission From Depressive Symptoms Among Older Adults With Mood Disord...
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Depressive Disorders in Primary Care: A Review
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Clinical features of psychogenic non-epileptic seizures in prepubertal...
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Comorbidities are Frequent in Patients with Gastroesophageal Reflux Di...
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Psychoeducational treatment and prevention of depression: The “coping ...
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Psychiatric admissions and hospitalization costs in bipolar disorder i...
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Recent developments in the epidemiology of bipolar disorder in adults ...
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Revisão das diretrizes da Associação Médica Brasileira para o tratamen...
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Mirtazapine
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Major Depression as a Risk Factor for High Blood Pressure: Epidemiolog...
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Treatments and issues of choice in depression
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Spezifische Behandlungsaspekte bipolar erkrankter Frauen
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Molecular epidemiology of major depressive disorder
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The global burden of mental disorders: An update from the WHO World Me...
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Trends in mental health of an adolescent medicine clinic patient popul...
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The role of religion in suicide prevention
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Psychological treatment of depression in primary care: a meta-analysis
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Classification, causes, and epidemiology
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How common are psychotic and bipolar disorders? A 50-year follow-up of...
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Medical Care Utilization Status and Associated Factors with Extended H...
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Prevalence of Co-Occurring Substance Use and other Mental Disorders in...
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Diagnosis and treatment in the early illness phase of bipolar disorder...
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Major Depression Prevalence is Very High, but the Syndrome is a Poor P...
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State and trait anxiety and depression in patients affected by gastroi...
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Evidence-based guidelines for treating depressive disorders with ...
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The Burden of Mental Disorders
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The Prevalence and Correlates of Workplace Depression in the National ...
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Clinical experience of the use of a pharmacological treatment algorith...
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Do Anxiety and Depression Confound Symptom Reporting and Diagnostic Ac...
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Cognitive Impairment Consequent to Motor Vehicle Collisions
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Barriers in the help-seeking process: A multiple-case study of early-o...
-
Depression and Suicidal Behavior in Acne Patients Treated With Isotret...
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An animated depiction of major depression epidemiology
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Prediction and prevention of suicide in patients with unipolar depress...
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Psychotic features in bipolar and unipolar depression
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Psychosomatic disturbances and cosmetic surgery
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Prevalence, Comorbidity, and Service Utilization for Mood Disorders in...
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Screeninginstrumente für Depressionen
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The Prevalence and Incidence of Treated Major Depressive Disorder amon...
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World Federation of Societies of Biological Psychiatry (WFSBP) Guideli...
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The acute treatment of bipolar depression: Historically relevant and r...
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Validity of the assessment of bipolar spectrum disorders in the WHO CI...
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Marital therapy for depression
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Cognition and Aging in Psychopathology: Focus on Schizophrenia and Dep...
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Descriptive Epidemiology of Major Depression in Canada
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Versorgungsforschung in der psychosozialen Medizin
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Ziprasidone alone or in combination for acute mania
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The Relevance of an Employee Assistance Program to the Treatment of Wo...
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Community Survey of Bipolar Disorder in Canada: Lifetime Prevalence an...
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Describing the longitudinal course of major depression using Markov mo...
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Lifetime risk of depression: restricted to a minority or waiting for m...
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Mental Health Problems of Army Personnel Seen in Medical Outpatient Cl...
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Canadian Depression Prevalence
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Drug resistance in brain diseases and the role of drug efflux transpor...
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Depresión e incremento de la prescripción de antidepresivos
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Depression and Suicidal Behavior in Acne Patients Treated With Isotret...
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Canadian Network for Mood and Anxiety Treatments (CANMAT) guidelines f...
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Duloxetine: pharmacoeconomic implications of an antidepressant that al...
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Treatment of neuropsychiatric syndromes in multiple sclerosis
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Prévalence et comorbidité des troubles psychiatriques dans la populati...
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Risperidone
-
Aripiprazole alone or in combination for acute mania
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Interventionspotenziale
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Affektive Störungen
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