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Dysregulated Smooth Muscle Cell BMPR2-ARRB2 Axis Causes Pulmonary Hypertension.
Wang L, Moonen JR, Cao A, Isobe S, Li CG, Tojais NF, Taylor S, Marciano DP, Chen PI, Gu M, Li D, Harper RL, El-Bizri N, Kim YM, Stankunas K, Rabinovitch M. Wang L, et al. Circ Res. 2023 Mar 3;132(5):545-564. doi: 10.1161/CIRCRESAHA.121.320541. Epub 2023 Feb 6. Circ Res. 2023. PMID: 36744494 Free PMC article.
From Model Organisms to Humans, the Opportunity for More Rigor in Methodologic and Statistical Analysis, Design, and Interpretation of Aging and Senescence Research.
Chusyd DE, Austad SN, Brown AW, Chen X, Dickinson SL, Ejima K, Fluharty D, Golzarri-Arroyo L, Holden R, Jamshidi-Naeini Y, Landsittel D, Lartey S, Mannix E, Vorland CJ, Allison DB. Chusyd DE, et al. J Gerontol A Biol Sci Med Sci. 2022 Nov 21;77(11):2155-2164. doi: 10.1093/gerona/glab382. J Gerontol A Biol Sci Med Sci. 2022. PMID: 34950945 Free PMC article. Review.
The following issues are addressed: (a) errors in randomization, (b) errors related to testing within-group instead of between-group differences, (c) failing to account for clustering, (d) failing to consider interference effects, (e) standardizing metrics of effect size, …
The following issues are addressed: (a) errors in randomization, (b) errors related to testing within-group instead of between-group differe …
Rewriting regulatory DNA to dissect and reprogram gene expression.
Martyn GE, Montgomery MT, Jones H, Guo K, Doughty BR, Linder J, Chen Z, Cochran K, Lawrence KA, Munson G, Pampari A, Fulco CP, Kelley DR, Lander ES, Kundaje A, Engreitz JM. Martyn GE, et al. bioRxiv [Preprint]. 2023 Dec 21:2023.12.20.572268. doi: 10.1101/2023.12.20.572268. bioRxiv. 2023. PMID: 38187584 Free PMC article. Preprint.
Strain-Sensitive Magnetization Reversal of a van der Waals Magnet.
Wang Y, Wang C, Liang SJ, Ma Z, Xu K, Liu X, Zhang L, Admasu AS, Cheong SW, Wang L, Chen M, Liu Z, Cheng B, Ji W, Miao F. Wang Y, et al. Adv Mater. 2020 Oct;32(42):e2004533. doi: 10.1002/adma.202004533. Epub 2020 Sep 13. Adv Mater. 2020. PMID: 32924236
In this study, a uniaxial tensile strain is applied to thin flakes of the vdW magnet Fe(3) GeTe(2) (FGT), and a dramatic increase of the coercive field (H(c) ) by more than 150% with an applied strain of 0.32% is observed. ...
In this study, a uniaxial tensile strain is applied to thin flakes of the vdW magnet Fe(3) GeTe(2) (FGT), and a dramatic increase of the coe …
Biomarker Panel for Chronic Graft-Versus-Host Disease.
Yu J, Storer BE, Kushekhar K, Abu Zaid M, Zhang Q, Gafken PR, Ogata Y, Martin PJ, Flowers ME, Hansen JA, Arora M, Cutler C, Jagasia M, Pidala J, Hamilton BK, Chen GL, Pusic I, Lee SJ, Paczesny S. Yu J, et al. J Clin Oncol. 2016 Aug 1;34(22):2583-90. doi: 10.1200/JCO.2015.65.9615. Epub 2016 May 23. J Clin Oncol. 2016. PMID: 27217465 Free PMC article.
Of 105 proteins showing at least a 1.25-fold difference in expression, 22 were selected on the basis of involvement in relevant pathways and enzyme-linked immunosorbent assay availability. Chemokine (C-X-C motif) ligand 9 (CXCL9) and suppression of tumorigenicity 2 …
Of 105 proteins showing at least a 1.25-fold difference in expression, 22 were selected on the basis of involvement in relevant pathways and …
HyPR-seq: Single-cell quantification of chosen RNAs via hybridization and sequencing of DNA probes.
Marshall JL, Doughty BR, Subramanian V, Guckelberger P, Wang Q, Chen LM, Rodriques SG, Zhang K, Fulco CP, Nasser J, Grinkevich EJ, Noel T, Mangiameli S, Bergman DT, Greka A, Lander ES, Chen F, Engreitz JM. Marshall JL, et al. Proc Natl Acad Sci U S A. 2020 Dec 29;117(52):33404-33413. doi: 10.1073/pnas.2010738117. Epub 2020 Dec 21. Proc Natl Acad Sci U S A. 2020. PMID: 33376219 Free PMC article.