Intake and serum levels of micronutrients and chronic oral diseases burden
Susilena Arouche Costa
Graduate Program in Dentistry, Federal University of Maranhão, São Luís, Brazil
Contribution: Conceptualization, Formal analysis, Methodology, Writing - original draft, Investigation
Search for more papers by this authorCorresponding Author
Gustavo G. Nascimento
National Dental Research Institute Singapore, National Dental Centre Singapore, Singapore City, Singapore
Oral Health ACP, Duke-NUS Medical School, Singapore City, Singapore
Correspondence
Gustavo G. Nascimento, National Dental Centre Singapore, 5 Second Hospital Ave, Singapore City 168938, Singapore.
Email: [email protected]
Contribution: Writing - review & editing, Visualization, Conceptualization, Formal analysis, Supervision
Search for more papers by this authorFábio R. M. Leite
National Dental Research Institute Singapore, National Dental Centre Singapore, Singapore City, Singapore
Oral Health ACP, Duke-NUS Medical School, Singapore City, Singapore
Contribution: Conceptualization, Writing - review & editing, Supervision, Visualization
Search for more papers by this authorCecilia Claudia Costa Ribeiro
Graduate Program in Dentistry, Federal University of Maranhão, São Luís, Brazil
Department of Public Health, Federal University of Maranhão, São Luís, Brazil
Contribution: Visualization, Writing - review & editing, Formal analysis, Supervision
Search for more papers by this authorSoraia de Fatima Carvalho Souza
Graduate Program in Dentistry, Federal University of Maranhão, São Luís, Brazil
Contribution: Visualization, Writing - review & editing, Formal analysis, Supervision
Search for more papers by this authorSusilena Arouche Costa
Graduate Program in Dentistry, Federal University of Maranhão, São Luís, Brazil
Contribution: Conceptualization, Formal analysis, Methodology, Writing - original draft, Investigation
Search for more papers by this authorCorresponding Author
Gustavo G. Nascimento
National Dental Research Institute Singapore, National Dental Centre Singapore, Singapore City, Singapore
Oral Health ACP, Duke-NUS Medical School, Singapore City, Singapore
Correspondence
Gustavo G. Nascimento, National Dental Centre Singapore, 5 Second Hospital Ave, Singapore City 168938, Singapore.
Email: [email protected]
Contribution: Writing - review & editing, Visualization, Conceptualization, Formal analysis, Supervision
Search for more papers by this authorFábio R. M. Leite
National Dental Research Institute Singapore, National Dental Centre Singapore, Singapore City, Singapore
Oral Health ACP, Duke-NUS Medical School, Singapore City, Singapore
Contribution: Conceptualization, Writing - review & editing, Supervision, Visualization
Search for more papers by this authorCecilia Claudia Costa Ribeiro
Graduate Program in Dentistry, Federal University of Maranhão, São Luís, Brazil
Department of Public Health, Federal University of Maranhão, São Luís, Brazil
Contribution: Visualization, Writing - review & editing, Formal analysis, Supervision
Search for more papers by this authorSoraia de Fatima Carvalho Souza
Graduate Program in Dentistry, Federal University of Maranhão, São Luís, Brazil
Contribution: Visualization, Writing - review & editing, Formal analysis, Supervision
Search for more papers by this authorAbstract
Objective
To investigate pathways from micronutrient intake and serum levels to Chronic Oral Diseases Burden.
Methods
We analyzed cross-sectional data from NHANES III (n = 7936) and NHANES 2011–2014 (n = 4929). The exposure was the intake and serum levels of vitamin D, calcium, and phosphorus. Considering the high correlation of those micronutrients in the diet, they were analyzed as a latent variable dubbed Micronutrient intake. The outcome was the Chronic Oral Diseases Burden, a latent variable formed by probing pocket depth, clinical attachment loss, furcation involvement, caries, and missing teeth. Pathways triggered by gender, age, socioeconomic status, obesity, smoking, and alcohol were also estimated using structural equation modeling.
Results
In both NHANES cycles, micronutrient intake (p-value < 0.05) and vitamin D serum (p-value < 0.05) were associated with a lower Chronic Oral Diseases Burden. Micronutrient intake reduced the Chronic Oral Diseases Burden via vitamin D serum (p-value < 0.05). Obesity increased the Chronic Oral Diseases Burden by reducing vitamin D serum (p-value < 0.05).
Conclusion
Higher micronutrient intake and higher vitamin D serum levels seem to reduce Chronic Oral Diseases Burden. Healthy diet policies may jointly tackle caries, periodontitis, obesity, and other non-communicable diseases.
CONFLICT OF INTEREST STATEMENT
The authors declare no conflict of interest, and no financial and personal relations that could influence the work.
Open Research
DATA AVAILABILITY STATEMENT
The data that support the findings of this study are openly available in National Center for Health Statistics at https://wwwn.cdc.gov/nchs/nhanes.
Supporting Information
| Filename | Description |
|---|---|
| odi14640-sup-0001-Supinfo.docxWord 2007 document , 23.7 KB | Appendix S1 |
| odi14640-sup-0002-FigureS1.docxWord 2007 document , 218.2 KB | Figure S1 |
| odi14640-sup-0003-TableS1.docxWord 2007 document , 15.4 KB | Table S1 |
| odi14640-sup-0004-TableS2.docxWord 2007 document , 13.7 KB | Table S2 |
Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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