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Original Articles

Adolescent Cannabis Misuse Scale: Longitudinal Associations with Substance Use, Mental Health, and Social Determinants of Health in Early Adulthood

ORCID Icon, , , &
Pages 1080-1089 | Published online: 09 May 2023
 

Abstract

Background

Some patterns of cannabis use may presage risk for long-term negative effects. We examined associations between a novel adolescent cannabis misuse scale and early-adult life course outcomes.

Methods

We performed a secondary data analysis of a cohort of Los Angeles, CA high school students from grade 9 through age 21. Participants reported baseline individual demographic and family characteristics at grade 9, adolescent cannabis misuse (8-items) and alcohol misuse (12-items) at grade 10, and outcomes at age 21. We used multivariable regression to model the associations of cannabis misuse scale score with problem substance use (defined as any of: 30-day illegal drug use, 30-day use of another’s prescription to get high, hazardous drinking) and several secondary outcomes (behavioral, mental health, academic, social determinants of health), adjusting for covariates. Parallel analyses were conducted for alcohol misuse.

Results

The 1,148 participants (86% retention) were 47% male, 90% Latinx, 87% US born, and 40% native English speakers. Approximately 11.4% and 15.9% of participants reported at least one item on the cannabis and alcohol misuse scales, respectively. At age 21, approximately 6.7% of participants reported problem substance use, which was associated with both Cannabis and Alcohol Misuse Scales (OR 1.31, 95%CI[1.16, 1.49] and OR 1.33, 95%CI[1.18, 1.49], respectively). Both scales were similarly associated with outcomes in all four categories.

Conclusions

The Adolescent Cannabis Misuse Scale is a promising tool for identifying early patterns of substance use that predict future negative outcomes and enabling early intervention at a critical period in youth development.

Acknowledgements

We would like to acknowledge the RISE-Up study staff and youth participants who made this research possible.

Declaration of interest

The authors report there are no competing interests to declare.

Data availability statement

The raw data supporting the conclusions of this article will be made available upon request to the senior author by emailing MitchellWong@mednet.ucla.edu.

Additional information

Funding

This work was supported by the National Institutes of Health (R01DA033362, KL2TR001882) and the Health Resources and Services Administration (UA6MC32492). The funders had no role in the study’s design, data collection, analysis, interpretation of the data, writing of the manuscript, or decision to submit the article for publication.

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