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Abstract

Background: Adolescents and young adults (AYA) from diverse and marginalized backgrounds with type 1 diabetes (T1D) generally have higher hemoglobin A1c (HbA1c) levels and less frequent continuous glucose monitor (CGM) use than AYA from more privileged backgrounds. Further, scant data address the impact of virtual peer groups (VPG) on health-related outcomes for ethnically and racially diverse AYA with T1D.
Methods: CoYoT1 to California was a 15-month randomized controlled trial for AYA aged 16–25 years. In this study, AYA were randomized to receive standard care (n = 28), or CoYoT1 care (n = 40), which consisted of person-centered provider visits and bimonthly VPG. VPG were AYA-driven discussions. AYA completed the Diabetes Distress Scale (DDS), Center for Epidemiologic Studies Depression (CES-D), and Diabetes Empowerment Scale-Short Form (DES-SF) scales at baseline and all study visits.
Results: Participants were 50% Latinx and 75% publicly insured. Among CoYoT1 care participants, 19 attended at least 1 VPG session (VPG attendees) and 21 did not attend any VPG sessions. VPG attendees participated in 4.1 VPG sessions on average. VPG attendees had a relative reduction in HbA1C (treatment effect −1.08%, effect sizes values [ES] = −0.49, P = 0.04) and increase in CGM use (treatment effect +47%, ES = 1.00, P = 0.02) compared to standard care. VPG participation was not associated with statistically significant changes in DDS, CES-D, and DES-SF scores.
Conclusions: In a 15-month randomized controlled trial, AYA with T1D who participated in VPG reported significant improvements in HbA1c and CGM use. Peer interactions may support unmet needs of AYA with T1D from diverse and marginalized backgrounds. ClinicalTrials.gov Identifier: NCT03793673.

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Information & Authors

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cover image Diabetes Technology & Therapeutics
Diabetes Technology & Therapeutics
Volume 25Issue Number 9September 2023
Pages: 589 - 601
PubMed: 37335751

History

Published in print: September 2023
Published online: 23 August 2023
Published ahead of print: 17 August 2023
Published ahead of production: 19 June 2023

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Affiliations

Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.
Mark W. Reid
Children's Hospital Los Angeles, Los Angeles, California, USA.
Elizabeth A. Pyatak
Chan Division of Occupational Science and Occupational Therapy, University of Southern California, Los Angeles, California, USA.
Jaquelin Flores Garcia
Children's Hospital Los Angeles, Los Angeles, California, USA.
Elizabeth Salcedo-Rodriguez
Children's Hospital Los Angeles, Los Angeles, California, USA.
Alejandra Torres Sanchez
Children's Hospital Los Angeles, Los Angeles, California, USA.
School of Pharmacy, University of Southern California, Los Angeles, California, USA.
Sarah Hiyari
Children's Hospital Los Angeles, Los Angeles, California, USA.
Jennifer L. Fogel
Children's Hospital Los Angeles, Los Angeles, California, USA.
Ian Marshall
Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.
Gloria Bachmann
Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.
Children's Hospital Los Angeles, Los Angeles, California, USA.
Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Notes

This study was presented in poster format at the 82nd Scientific Sessions of the American Diabetes Association, New Orleans, LA, June 3–7, 2022.
Address correspondence to: Jennifer K. Raymond, MD, MCR, Children's Hospital Los Angeles, Los Angeles, CA 90027, USA [email protected]
Daniel I. Bisno, BA, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA [email protected]

Authors' Contributions

D.I.B. conceived this analysis and prepared the initial article draft. M.W.R. designed and ran the statistical analyses. J.K.R. conceived, designed, and directed the underlying study. All authors contributed to results interpretation, discussion, and review/editing of the article.

Author Disclosure Statement

No competing financial interests exist.

Funding Information

This work was funded by The Patrick and Catherine Weldon Donaghue Medical Research Foundation.

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