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Adipose Tissue: From Energy Reservoir to a Source of Cells for Epithelial Tissue Engineering

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Stem Cells in Aesthetic Procedures

Abstract

Adipose tissue is accessible with minimally invasive procedures, is abundant, and is replenishable. It consists of a heterogeneous cell population including preadipocytes, mature adipocytes, fibroblasts, vascular smooth muscle cells, endothelial cells, resident macrophages, and cells composing the stromal vascular fraction. This fraction contains multipotent cells with the same mesenchymal origin and similar biological and immunological characteristics of bone marrow stroma. On the other hand, adipose-derived stromal cells are easier to harvest and culture in comparison to bone marrow-derived ones. The authors discuss the microenvironment where are the stem cells is the niche, adipose tissue, and adipose tissue-derived stromal cell transplant for the treatment of epithelial pathologies, wound healing, diabetic foot, and other disorders.

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Authors and Affiliations

  1. Department of Surgical Science, University “Sapienza”, Rome, Italy

    Angelo Trivisonno M.D., Ph.D. & Massimo Monti M.D.

  2. Private Practice, 6 Place de la Republique Dominicaine, Paris, 75017, France

    Marc Abecassis M.D.

  3. Molecular Oncogenesis Laboratory, Istituto Nazionale dei Tumori Regina Elena, Rome, Italy

    Gabriele Toietta Ph.D.

  4. Service Chirurgie Plastique Hopital, Saint Louis, Paris, France

    Athmani Bachir M.D.

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  1. Angelo Trivisonno M.D., Ph.D.
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  2. Marc Abecassis M.D.
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  3. Massimo Monti M.D.
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  4. Gabriele Toietta Ph.D.
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  5. Athmani Bachir M.D.
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Correspondence to Angelo Trivisonno M.D., Ph.D. .

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Editors and Affiliations

  1. Section of Surgery, Newport Specialty Hospital, Tustin, California, USA

    Melvin A. Shiffman

  2. Department of Plastic and Reconstructive Surgery, Marche Polytechnic University Medical School, University of Ancona, Ancona, Italy

    Alberto Di Giuseppe

  3. Department of Plastic Surgery, University of Padova, Padova, Italy

    Franco Bassetto

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Trivisonno, A., Abecassis, M., Monti, M., Toietta, G., Bachir, A. (2014). Adipose Tissue: From Energy Reservoir to a Source of Cells for Epithelial Tissue Engineering. In: Shiffman, M., Di Giuseppe, A., Bassetto, F. (eds) Stem Cells in Aesthetic Procedures. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-45207-9_21

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