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Association between oral frailty and lower urinary tract symptoms among middle-aged and older adults in community-dwelling individuals: a cross-sectional study

  • Urology - Original Paper
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Abstract

Purpose

We assessed the association between oral frailty risk and LUTS among middle-aged and older adults in a community-dwelling population.

Methods

This cross-sectional study was conducted among 586 subjects aged ≥ 40 years who participated in the Iwaki Health Promotion Project in Hirosaki, Japan. We used the International Prostate Symptom Score (IPSS) and the Overactive Bladder Symptom Score (OABSS) to assess LUTS. LUTS was defined as an IPSS score of 8 or higher or meeting diagnostic criteria for OAB. Oral frailty risk was defined as experiencing two or more of the following: decreased chewing ability, decreased biting force, and dry mouth sensation. Physical performance (10-m gait speed and grip strength) was used for analysis. The association between oral frailty risk and LUTS was examined using multivariate logistic regression analyses.

Results

The study included 218 men and 370 women, of whom 140 had LUTS. The mean age of this cohort was 59 years. Significant differences were observed between the LUTS and non-LUTS groups, including age, hypertension, history of CVD, depressive status, sleep disturbance, and 10 m gait speed. The prevalence of oral frailty risk was significantly higher in the LUTS group than in the non-LUTS group (26% vs. 11%, P < 0.001). Multivariate analysis revealed that age, male gender, and oral frailty risk (odds ratio: 2.67, 95% confidence interval: 1.57–4.51, P < 0.001) were independent factors for LUTS. Moreover, oral frailty risk was an independent factor in both participants aged < 65 years and participants aged ≥ 65 years.

Conclusions

Oral frailty was independently associated with LUTS.

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Acknowledgements

All authors have contributed significantly to this work. We would like to thank the entire staff of the Department of Social Medicine and Department of Oral and Maxillofacial Surgery in Hirosaki University for their invaluable help with the collection of data. This work was supported by JST Grant Number JPMJCE1302, JPMJCA2201, and JPMJPF2210.

Funding

None to declare.

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Authors and Affiliations

  1. Department of Urology, Hirosaki University Graduate School of Medicine, 5 Zaifu-Chou, Hirosaki, 036-8562, Japan

    Fumiya Yoneyama, Teppei Okamoto, Noritaka Ishii, Kyo Togashi, Osamu Soma, Naoki Fujita, Hayato Yamamoto, Shingo Hatakeyama & Chikara Ohyama

  2. Department of Oral and Maxillofacial Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu-Chou, Hirosaki, 036-8562, Japan

    Yoshihiro Tamura & Wataru Kobayashi

  3. Department of Advanced Transplant and Regenerative Medicine, Hirosaki University Graduate School of Medicine, Hirosaki, Japan

    Chikara Ohyama

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  1. Fumiya Yoneyama
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Correspondence to Teppei Okamoto.

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Yoneyama, F., Okamoto, T., Tamura, Y. et al. Association between oral frailty and lower urinary tract symptoms among middle-aged and older adults in community-dwelling individuals: a cross-sectional study. Int Urol Nephrol 56, 1803–1810 (2024). https://doi.org/10.1007/s11255-023-03878-6

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