Volume 15, Issue 1 p. 152-171
ORIGINAL ARTICLE

Loneliness predicts physical and mental health-related quality of life over 9 months among patients with coronary heart disease

Yunge Fan

Yunge Fan

Psychology Programme, School of Social Sciences, Nanyang Technological University, Singapore

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Moon-Ho Ringo Ho

Corresponding Author

Moon-Ho Ringo Ho

Psychology Programme, School of Social Sciences, Nanyang Technological University, Singapore

Correspondence

Ho Moon-Ho Ringo, Psychology Programme, School of Social Sciences, Nanyang Technological University, 48 Nanyang Avenue. Singapore 639818.

Email: [email protected]

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Biing-Jiun Shen

Biing-Jiun Shen

The Wright Institute, Berkeley, California, USA

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First published: 02 October 2022
Citations: 4

Funding information:

This study was supported by the Singapore Ministry of Education Academic Research Fund Tier 1 Grant (RG60/14) and a STAUG award from Nanyang Technological University.

Abstract

This study investigated whether loneliness would predict physical and mental health-related quality of life (HRQoL) over 9 months and examined whether medical adherence would mediate their associations in patients with coronary heart disease (CHD). The overall design is a three-wave longitudinal study. A sample of 255 outpatients with CHD was recruited from a community-based cardiac rehabilitation programme. Participants, with a mean age of 63 years, completed measures assessing loneliness, depression and physical and mental HRQoL at baseline. Medical adherence was assessed at 3 months, and physical and mental HRQoL were reassessed at 9 months. A total of 88% of participants reported moderate or high loneliness. Baseline loneliness predicted physical and mental HRQoL at 9 months after adjusting for baseline physical and mental HRQoL, respectively. The effects remained significant when depression was also adjusted. Medical adherence at 3 months partially mediated the associations of baseline loneliness with 9-month physical and mental HRQoL. Findings underline the necessity of assessing loneliness for CHD patients to promote long-term medical adherence and further improve physical and mental HRQoL.