An Evolutionary Analysis of Antigen Processing and Presentation across Different Timescales Reveals Pervasive Selection
Figure 1
STRING interaction diagram of the analyzed genes.
Classic HLA class I and class II genes are also shown (although not analyzed). Each filled node denotes a gene; edges between nodes indicate interactions between protein products of the corresponding genes. Different edge colors represent the types of evidence for the association. Annotation of genes and gene clusters refers to their major activity/location in APP. Genes are colored according to the observed selection signatures either described herein or in previous works [33], [43], [44].