romila karnawat

Pesticides are major contaminating chemicals in agriculture environment and a hazard to exposed population. The pesticides form a strong class of environment pollutants, as they are sometimes nonbiodegradable, damaged not only the environment and agriculture but also have entered into the food chain thereby affecting health and development. Methyl parathion is a broad-spectrum organophosphorus insecticide generally used to control a variety of insects. The present study was planned to develop a new method for analysis of Methyl parathion in human blood samples using thin layer chromatography technique, which is simple and quick. Methyl Parathion was extracted from blood using solvent extraction methods and then identified on the TLC plates. For chromatographic separation, various binary and tertiary solvent systems were used and for detection on developed plates, palladium chloride reagent was used which successfully increased the sensitivity without dispensing with the simplicity o...

In this study, a series of azo compounds were synthesized in excellent yields via the diazotization of different aromatic amines followed by coupling with 2-naphthol. These compounds were characterized by elemental analysis, IR, 1 H NMR and 13 C NMR spectral techniques. The synthesized compounds have been tested in vitro against a number of microorganisms in order to assess their antimicrobial properties using disk diffusion method. The minimum inhibitory concentrations (MIC) were also determined by the broath microdilution technique. Some of the products exhibited comparable activity with known standard drugs at same concentration. Keyword: 4-hydroxy-1-naphthalenesulphonic acid, Antimicrobial, Disc diffusion, Broath dilution.

The synthesis and characterization of a series of hydroxamic acids derived from benzoylation or acylation of substituted aryl hydroxylamine or hydroxylamine hydrochloride are reported. Elemental analysis, 1 H NMR, 13 C NMR, and IR spectral data of the compounds are

2-Phenylazo-1-naphthol-4-sulphonicacid (PANS) was synthesized and characterized by IR, HNMRand C NMR spectral techniques. The electrochemical behaviour of PANS was studied using cyclic voltammetry and constant current electrolysis. The effect of scan rate and pH on the reduction peaks has been studied. The voltammogram recorded at glassy carbon electrode (GCE) in acidic, neutral and basic media at different scan rates exhibit one or two cathodic peaks depending on the pH of the medium. The kinetic parameters were also calculated and the process was found to be diffusion controlled. The reaction mechanism for the reduction is proposed on the basis of obtained voltammograms and constant current electrolysis data. The antibacterial activity of PANS was tested in vitro against a number of microorganisms.

Pathogenic fungi are the main infectious agents in plants, causing alterations during developmental stages including post-harvest. Plants have been explored extensively all over the globe in quest of a novel bioactive compound that could a good therapeutic candidate treating infectious diseases especially against drug resistant microbes. Plants are a rich source of novel natural substances that can be used to develop environmental safe method for fungus control. In the present study the efficacy of organic extracts of Catharanthus roseus, Ricinus communis, Carrica papaya and Annona squammosa leaves against the pathogenic fungus i.e Aspergillus niger, Thrichoderma reesei, Penicillium fumiculosum were studied in vitro by agar well diffusion assay. Nearly all the extracts were found effective against these fungi. The positive results so obtained were compared with that of the reference standard fungicide (Matco 8–64 and Ketoconazole). It was found that most of the extracts were found m...