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11 result(s) for 'author#Nicolas Chomont' within BMC
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Citation: Infectious Agents and Cancer 2022 17(Suppl 1):36
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Conference highlights of the 5th international workshop on HIV persistence during therapy, 6-9 December 2011, St. Maartin, West Indies
The December 2011 5th International Workshop on HIV Persistence during Therapy addressed the issue of HIV persistence among 210 scientists from 10 countries involved in the study of HIV reservoirs and the search ...
Citation: AIDS Research and Therapy 2012 9:7 -
Workshop report: “Towards a Cure: HIV Reservoirs and Strategies to Control Them”
On 16 and 17 July 2010, immediately prior to the XVIII International AIDS Conference in Vienna, Austria, the International AIDS Society held a workshop on the important topic of moving beyond antiretroviral th...
Citation: Journal of the International AIDS Society 2010 13(Suppl 3):I1 -
A novel acute HIV infection staging system based on 4thgeneration immunoassay
Fourth generation (4thG) immunoassay (IA) is becoming the standard HIV screening method but was not available when the Fiebig acute HIV infection (AHI) staging system was proposed. Here we evaluated AHI stagin...
Citation: Retrovirology 2013 10:56 -
Optimizing the World Health Organization algorithm for HIV vertical transmission risk assessment by adding maternal self-reported antiretroviral therapy adherence
The World Health Organization (WHO) risk assessment algorithm for vertical transmission of HIV (VT) assumes the availability of maternal viral load (VL) result at delivery and early viral control 4 weeks after...
Citation: BMC Public Health 2022 22:1312 -
Inducible HIV RNA transcription assays to measure HIV persistence: pros and cons of a compromise
With the increasing number of therapeutic strategies tested in humans to reduce the size of the latent reservoir, the development of a robust, precise and clinical trial scalable assay that measures the freque...
Citation: Retrovirology 2018 15:9 -
New insights into the heterogeneity of Th17 subsets contributing to HIV-1 persistence during antiretroviral therapy
Th17 cells are permissive to HIV-1 infection and their depletion from the gut of infected individuals leads to microbial translocation, a major cause for non-AIDS co-morbidities. Most recent evidence supports ...
Citation: Retrovirology 2016 13:59 -
Identification of novel HIV-1 dependency factors in primary CCR4+CCR6+Th17 cells via a genome-wide transcriptional approach
The HIV-1 infection is characterized by profound CD4+ T cell destruction and a marked Th17 dysfunction at the mucosal level. Viral suppressive antiretroviral therapy restores Th1 but not Th17 cells. Although sev...
Citation: Retrovirology 2015 12:102 -
Finding a cure for HIV: will it ever be achievable?
Combination antiretroviral therapy (cART) has led to a major reduction in HIV-related mortality and morbidity. However, HIV still cannot be cured. With the absence of an effective prophylactic or therapeutic v...
Citation: Journal of the International AIDS Society 2011 14:4 -
Impaired Th17 polarization of phenotypically naive CD4+ T-cells during chronic HIV-1 infection and potential restoration with early ART
Depletion of mucosal Th17 cells during HIV/SIV infections is a major cause for microbial translocation, chronic immune activation, and disease progression. Mechanisms contributing to Th17 deficit are not fully...
Citation: Retrovirology 2015 12:38 -
ushr: Understanding suppression of HIV in R
HIV/AIDS is responsible for the deaths of one million people every year. Although mathematical modeling has provided many insights into the dynamics of HIV infection, there is still a lack of accessible tools ...
Citation: BMC Bioinformatics 2020 21:52