Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization.
J Neurosci. 2004 Sep 22;24(38):8310-21. doi: 10.1523/JNEUROSCI.2396-04.2004. J Neurosci. 2004. PMID: 15385614 Free PMC article.