Volume 65, Issue 5 p. 518-528
Medical Imaging—Review Article

Artificial intelligence in clinical decision support and outcome prediction – applications in stroke

Melissa Yeo

Corresponding Author

Melissa Yeo

School of Medicine, University of Melbourne, Melbourne, Victoria, Australia

Correspondence

Dr Melissa Yeo, Ground Floor, Medical Building, Cnr Grattan Street & Royal Parade, University of Melbourne, Vic 3010, Australia.

Email: [email protected]

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Hong Kuan Kok

Hong Kuan Kok

Interventional Radiology Service, Department of Radiology, Northern Health, Melbourne, Victoria, Australia

School of Medicine, Faculty of Health, Deakin University, Burwood, Victoria, Australia

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Numan Kutaiba

Numan Kutaiba

Department of Radiology, Austin Hospital, Melbourne, Victoria, Australia

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Julian Maingard

Julian Maingard

School of Medicine, Faculty of Health, Deakin University, Burwood, Victoria, Australia

Interventional Neuroradiology Unit, Monash Health, Clayton, Victoria, Australia

Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia

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Vincent Thijs

Vincent Thijs

Stroke Theme, Florey Institute of Neuroscience and Mental Health, Melbourne, Victoria, Australia

Department of Neurology, Austin Health, Melbourne, Victoria, Australia

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Bahman Tahayori

Bahman Tahayori

Department of Biomedical Engineering, The University of Melbourne, Melbourne, Victoria, Australia

IBM Research Australia, Melbourne, Victoria, Australia

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Jeremy Russell

Jeremy Russell

Department of Neurosurgery, Austin Hospital, Melbourne, Victoria, Australia

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Ashu Jhamb

Ashu Jhamb

Department of Radiology, St Vincent’s Hospital, Melbourne, Victoria, Australia

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Ronil V. Chandra

Ronil V. Chandra

Interventional Neuroradiology Unit, Monash Health, Clayton, Victoria, Australia

Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia

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Mark Brooks

Mark Brooks

School of Medicine, University of Melbourne, Melbourne, Victoria, Australia

School of Medicine, Faculty of Health, Deakin University, Burwood, Victoria, Australia

Stroke Theme, Florey Institute of Neuroscience and Mental Health, Melbourne, Victoria, Australia

Interventional Neuroradiology Service, Department of Radiology, Austin Hospital, Melbourne, Victoria, Australia

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Christen D. Barras

Christen D. Barras

South Australian Institute of Health and Medical Research, Adelaide, South Australia, Australia

School of Medicine, The University of Adelaide, Adelaide, South Australia, Australia

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Hamed Asadi

Hamed Asadi

School of Medicine, Faculty of Health, Deakin University, Burwood, Victoria, Australia

Interventional Neuroradiology Unit, Monash Health, Clayton, Victoria, Australia

Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia

Stroke Theme, Florey Institute of Neuroscience and Mental Health, Melbourne, Victoria, Australia

Department of Radiology, St Vincent’s Hospital, Melbourne, Victoria, Australia

Interventional Neuroradiology Service, Department of Radiology, Austin Hospital, Melbourne, Victoria, Australia

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First published: 28 May 2021
Citations: 9
M Yeo MD; HK Kok MB, BMedSci, MRCPI, MRCP(UK), FFR RCSI, FRCR, FRANZCR, EBIR; N Kutaiba MBChB, MMed, FRANZCR; J Maingard MBBS, BBiomedSci, FRANZCR; V Thijs MD, PhD; B Tahayori PhD; J Russell BSc/BE (Hons), MBBS (Hons), FRACS; A Jhamb MBBS (Hons), FRANZCR, EBIR, CCINR; RV Chandra MBBS, MMed, FRANZCR, CCINR; M Brooks MBBS, FRANZCR, CCINR, EBIR; CD Barras MBBS (Hons), BMedSc (Hons), MMed, PhD, FRANZCR; H Asadi MD, PhD, FRANZCR, CCINR, EBIR, FCIRSE.
Conflict of interest: The authors have no conflicts of interest to disclose.

Summary

Artificial intelligence (AI) is making a profound impact in healthcare, with the number of AI applications in medicine increasing substantially over the past five years. In acute stroke, it is playing an increasingly important role in clinical decision-making. Contemporary advances have increased the amount of information – both clinical and radiological – which clinicians must consider when managing patients. In the time-critical setting of acute stroke, AI offers the tools to rapidly evaluate and consolidate available information, extracting specific predictions from rich, noisy data. It has been applied to the automatic detection of stroke lesions on imaging and can guide treatment decisions through the prediction of tissue outcomes and long-term functional outcomes. This review examines the current state of AI applications in stroke, exploring their potential to reform stroke care through clinical decision support, as well as the challenges and limitations which must be addressed to facilitate their acceptance and adoption for clinical use.

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