HOW WE DO IT

Injection Necrosis of the Glabella

Protocol for Prevention and Treatment After Use of Dermal Fillers

GLAICH, ADRIENNE S. MD*; COHEN, JOEL L. MD†,‡; GOLDBERG, LEONARD H. MD, FRCP*,§

Author Information

*DermSurgery Associates, Houston, TX

†AboutSkin Dermatology, Denver, CO

‡Department of Dermatology, University of Colorado, Denver, CO

§Department of Medicine (Dermatology), University of Texas, MD Anderson Cancer Center, Houston, TX

Address correspondence and reprint requests to: Leonard H. Goldberg, MD, DermSurgery Associates, 7515 Main Street, Suite 240, Houston, TX 77030, or e-mail: [email protected].

Adrienne S. Glaich, MD, Joel L. Cohen, MD, and Leonard H. Goldberg, MD, FRCP, have indicated no significant interest with commercial supporters.

Dermatologic Surgery 32(2):p 276-281, February 2006.

Abstract

BACKGROUND 

Injection of filler materials into the dermis is well tolerated with few mild and transient side effects. Injection necrosis is a rare but clinically important potential complication caused by interruption of the vascular supply to the area by compression, injury, and/or obstruction of the vessel(s). The glabella is a particular danger zone for injection necrosis regardless of the type of filler used.

OBJECTIVE 

We recommend a protocol that may be used to help prevent and treat injection necrosis of the glabella after injection with dermal fillers.

CONCLUSION 

Injection necrosis in the glabellar region may be prevented by a knowledge of the local anatomy and an understanding of its pathophysiology and treated by a suggested protocol.

© 2006 by the American Society for Dermatologic Surgery, Inc.

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