Abstract
Cases of central nervous system demyelination have been reported after recombinant hepatitis B vaccination, but no causal link has been clearly demonstrated. We present the first case report involving the occurrence of 2 episodes of leukoencephalitis in a previously healthy patient after vaccination and rechallenge with hepatitis B vaccine.
MeSH terms
- Adult
- Brain / diagnostic imaging
- Female
- Hepatitis B / genetics
- Hepatitis B / prevention & control
- Hepatitis B Vaccines / adverse effects*
- Hepatitis B virus / immunology
- Humans
- Leukoencephalitis, Acute Hemorrhagic / chemically induced*
- Leukoencephalitis, Acute Hemorrhagic / diagnostic imaging*
- Magnetic Resonance Imaging
- Radiography
- Recombination, Genetic / genetics
- Vaccination