Focal hyperhidrosis: diagnosis and management

CMAJ. 2005 Jan 4;172(1):69-75. doi: 10.1503/cmaj.1040708.

Abstract

Hyperhidrosis, a condition characterized by excessive sweating, can be generalized or focal. Generalized hyperhidrosis involves the entire body and is usually part of an underlying condition, most often an infectious, endocrine or neurologic disorder. Focal hyperhidrosis is idiopathic, occurring in otherwise healthy people. It affects 1 or more body areas, most often the palms, armpits, soles or face. Almost 3% of the general population, largely people aged between 25 and 64 years, experience hyperhidrosis. The condition carries a substantial psychological and social burden, since it interferes with daily activities. However, patients rarely seek a physician's help because many are unaware that they have a treatable medical disorder. Early detection and management of hyperhidrosis can significantly improve a patient's quality of life. There are various topical, systemic, surgical and nonsurgical treatments available with efficacy rates greater than 90%-95%.

Publication types

  • Review

MeSH terms

  • Administration, Topical
  • Aluminum Chloride
  • Aluminum Compounds / therapeutic use
  • Botulinum Toxins, Type A / therapeutic use
  • Chlorides / therapeutic use
  • Humans
  • Hyperhidrosis / diagnosis*
  • Hyperhidrosis / epidemiology
  • Hyperhidrosis / physiopathology
  • Hyperhidrosis / therapy*
  • Iontophoresis
  • Neuromuscular Agents / therapeutic use
  • Sympathectomy

Substances

  • Aluminum Compounds
  • Chlorides
  • Neuromuscular Agents
  • Aluminum Chloride
  • Botulinum Toxins, Type A