Treatment of ocular rosacea

Surv Ophthalmol. 2018 May-Jun;63(3):340-346. doi: 10.1016/j.survophthal.2017.07.005. Epub 2017 Aug 4.

Abstract

Although rosacea is a common entity with significant cosmetic, socioeconomic, and vision-threatening impacts, this disorder remains incurable. Furthermore, until quite recently many of the therapeutic options for rosacea had not been assessed through rigorous clinical testing with meaningful outcome measures. Nonetheless, new medical and surgical interventions that have been validated in well-designed trials hold the promise of treating rosacea more effectively. Furthermore, recent enhancements in our understanding of the cellular and molecular biology offer highly translational insights that will hopefully lead to the development of new treatment options for rosacea. We review the evidence for these therapies and discuss new scientific findings that can be exploited for new therapeutic interventions.

Keywords: dry eye; eyelid; meibomian gland disease; ocular surface disease; rosacea.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Corneal Diseases / etiology
  • Corneal Diseases / therapy*
  • Diet Therapy
  • Dry Eye Syndromes / etiology
  • Dry Eye Syndromes / therapy*
  • Eyelid Diseases / etiology
  • Eyelid Diseases / therapy*
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Laser Therapy / methods
  • Lubricant Eye Drops / therapeutic use
  • Meibomian Glands
  • Ophthalmologic Surgical Procedures
  • Photophobia / etiology
  • Photophobia / therapy*
  • Rosacea / complications
  • Rosacea / therapy*
  • Tears / metabolism

Substances

  • Anti-Bacterial Agents
  • Immunosuppressive Agents
  • Lubricant Eye Drops