Large-scale whole-genome resequencing unravels the domestication history of Cannabis sativa
Abstract
INTRODUCTION
RESULTS AND DISCUSSION
Population genetic analyses
Demographic history
Selection signatures during domestication and improvement
Loss of function of the two main cannabinoid synthase genes during domestication
Conclusion
MATERIALS AND METHODS
Samples, sequencing, quality control, and mapping
Filtering alignments
SNP and genotype calling
Relatedness analysis
Population structure analysis
Demographic history
Linkage disequilibrium analyses
Genome-wide patterns of divergence, heterozygosity, and nucleotide diversity
Screening for selective sweeps
Annotation of selective sweeps
Presence/absence and variation of THCAS and CBDAS
Acknowledgments
Supplementary Materials
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July 2021
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- Guangpeng Ren et al.
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