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First published online November 1, 2008

Hemorheological Disorders in Diabetes Mellitus

Young I. Cho, Ph.D. [email protected], Michael P. Mooney, B.S., and Daniel J. Cho, B.A.View all authors and affiliations
Volume 2, Issue 6
https://doi.org/10.1177/193229680800200622

Abstract

The objective of the present study is to review hemorheological disorders in diabetes mellitus. Several key hemorheological parameters, such as whole blood viscosity, erythrocyte deformability, and aggregation, are examined in the context of elevated blood glucose level in diabetes. The erythrocyte deformability is reduced, whereas its aggregation increases, both of which make whole blood more viscous compared to healthy individuals. The present paper explains how the increased blood viscosity adversely affects the microcirculation in diabetes, leading to microangiopathy.

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Published In

Volume 2, Issue 6
Pages: 1130 - 1138
Article first published online: November 1, 2008
Issue published: November 2008

Keywords

  1. hemorheological disorders
  2. blood viscosity
  3. erythrocyte deformability and aggregation
  4. diabetes mellitus
  5. microangiopathy

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© 2008 Diabetes Technology Society.
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PubMed: 19885302

Authors

Affiliations

Young I. Cho, Ph.D.
Author Affiliations: Department of Mechanical Engineering and Mechanics, Drexel University, Philadelphia, Pennsylvania
[email protected]
View all articles by this author
Michael P. Mooney, B.S.
Rheologics Incorporated, Exton, Pennsylvania
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Daniel J. Cho, B.A.
Rheologics Incorporated, Exton, Pennsylvania
View all articles by this author

Notes

Corresponding Author: Young I. Cho, Ph.D., Department of Mechanical Engineering and Mechanics, Drexel University, 3141 Chestnut Street, Philadelphia, PA 19104; email address [email protected]

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