Beware of manipulations on the genome: epigenetic destabilization through (foreign) DNA insertions

Epigenomics. 2016 May;8(5):587-91. doi: 10.2217/epi-2016-0019. Epub 2016 Mar 21.
No abstract available

Keywords: DNA methylation; biology and the concepts of dark energy and dark matter; epigenetic consequences and evolution; epigenetic consequences of foreign DNA insertions; epigenetic mechanisms of oncogenesis; epigenetic sequelae of genome manipulations; food ingested DNA; foreign DNA integration into mammalian genomes; hypothesis on DNA as recipient for cosmic emissions; transcriptional profiles.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Animals, Genetically Modified
  • Bioengineering / methods
  • Bioengineering / trends
  • DNA Transposable Elements / physiology*
  • Epigenesis, Genetic / physiology*
  • Genome / genetics*
  • Genomic Instability*
  • Humans
  • Mice
  • Mutagenesis, Insertional / genetics
  • Mutagenesis, Insertional / methods
  • Mutagenesis, Insertional / physiology*

Substances

  • DNA Transposable Elements