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Environmental factors and unhealthy lifestyle influence oxidative stress in humans—an overview

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Abstract

Oxygen is the most essential molecule for life; since it is a strong oxidizing agent, it can aggravate the damage within the cell by a series of oxidative events including the generation of free radicals. Antioxidative agents are the only defense mechanism to neutralize these free radicals. Free radicals are not only generated internally in our body system but also trough external sources like environmental pollution, toxic metals, cigarette smoke, pesticides, etc., which add damage to our body system. Inhaling these toxic chemicals in the environment has become unavoidable in modern civilization. Antioxidants of plant origin with free radical scavenging properties could have great importance as therapeutic agents in several diseases caused by environmental pollution. This review summarizes the generation of reactive oxygen species and damage to cells by exposure to external factors, unhealthy lifestyle, and role of herbal plants in scavenging these reactive oxygen species.

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References

  • Akhgari M, Abdollahi M, Kebryaeezadeh A, Hosseini R, Sabzevari O (2003) Biochemical evidence for free radical-induced lipid peroxidation as a mechanism for subchronic toxicity of malathion in blood and liver of rats. Hum Exp Toxicol 22:205–211

    Article  CAS  Google Scholar 

  • Akimoto H (2003) Global air quality and pollution. Science 302:1716–1719

    Article  CAS  Google Scholar 

  • Akkus H (2011) Effects of acute exercise and aerobic exercise training on oxidative stress in young men and women. AJPP 5:1925–1931

    CAS  Google Scholar 

  • Alessio HM, Hangerman AE (2006) Oxidative stress, exercise and aging. Imperial College Press, London, pp 12–23

    Book  Google Scholar 

  • Alexandrov K, Rojas M, Rolando C (2006) DNA damage by benzo(a)pyrene in human cells is increased by cigarette smoke and decreased by a filter containing rosemary extract which lowers free radicals. Cigarette Smoke Free Radicals and BPDE-DNA Adduct 66(24):11517–12052

    Google Scholar 

  • Allen RG, Tresini M (2000) Oxidative stress and gene regulation. Free Radic Biol Med 28(3):463–499

    Article  CAS  Google Scholar 

  • Ambrose JA, Barua RS (2004) The pathophysiology of cigarette smoking and cardiovascular disease. An update J Am Coll Cardiol 43:1731–1737

    Article  CAS  Google Scholar 

  • Anetor JI, Adeniyi FAA (1998) Decreased immune status in Nigerian workers occupationally exposed to lead. Afr J Med Med Sci 28:169–172

    Google Scholar 

  • Aust SD, Chignell CF, Bray TM, Klayanaraman B, Mason RP (1993) Contemporary issues in toxicology free radicals in toxicology. Toxiocol Appl Pharmacol 120:168

    Article  CAS  Google Scholar 

  • Aydin S, Aral I, Kilic N, Bakan I, Aydin S, Erman F (2004) The level of antioxidant enzymes, plasma vitamins C and E in cement plant workers. Clin Chim Acta 341:193–198

    Article  CAS  Google Scholar 

  • Baan R, Straif K, Grosse Y, Secretan B, Ghissassi F, Bouvard V, Altieri A, Cogliano V (2007) Carcinogenicity of alcoholic beverages. The Lancet Oncol 8:292–293

    Article  Google Scholar 

  • Bagnardi V, Blangiardo M, La Vecchia C, Corrao G (2001) A meta analysis of alcohol drinking and cancer risk. Br J Cancer 85:1700–1705

    Article  CAS  Google Scholar 

  • Belinha I, Amorim MA, Rodrigues P, de Freitas V, Moradas-Ferreira P, Mateus N et al (2007) Quercetin increases oxidative stress resistance and longevity in Saccharomyces cerevisiae. J Agric Food Chem 55:2446–245

    Article  CAS  Google Scholar 

  • Bhalodia NR, Nariya PB, Acharya RN, Shukla VJ (2011) Evaluation of in vitro antioxidant activity of flowers of Cassia fistula Linn. Int J Pharm Tech Res 3:589–599

    Google Scholar 

  • Block ML, Calderón-Garcidueñas L (2009) Air pollution: mechanisms of neuroinflammation and CNS disease. Trends Neurosci 32(9):506–516

    Article  CAS  Google Scholar 

  • Bloomer RJ (2007) Decreased blood antioxidant capacity and increased lipid peroxidation in young cigarette smokers compared to nonsmokers: impact of dietary intake. Nutr J 6:39

    Article  CAS  Google Scholar 

  • Boffetta P, Hashibe M (2006) Alcohol and cancer. Lancet Oncol 7:149–156

    Article  CAS  Google Scholar 

  • Boring CC, Squires TS, Tong T (1993) Cancer statistics. Cancer Abs 43:7–26

    CAS  Google Scholar 

  • Bouayed J, Bohn T (2010) Endogenous-double-edged-swords in cellular redox state: health beneficial effects at physiologic doses versus deleterious effects at high dose. Oxid Med Cell Longev 3(4):228–237

    Article  Google Scholar 

  • Boubaker J, Mansour HB, Ghedira K, Chekir-Ghedira L (2011) Antimutagenic and free radical scavenger effects of leaf extracts from Accacia salicina. Contact Dermatitis 10:37–47

    Google Scholar 

  • Bressler J, Kim KA, Chakraborti T, Goldstein G (1999) Molecular mechanisms of lead neurotoxicity. Neurochem Res 24:595–600

    Article  CAS  Google Scholar 

  • Carson R (2002) Silent spring. First Mariner Books edition. Houghton Miflin Company, New York

    Google Scholar 

  • Chen F, Ding M, Castranova V, Shi XL (2001) Carcinogenic metals and NF-kappa B activation. Mol Cell Biochem 222:159–71

    Article  CAS  Google Scholar 

  • Chen F, Shi X (2002) Signaling from toxic metals to NF-B and beyond: not just a matter of reactive oxygen species. Environ Health Perspect 110:807–811

    Article  CAS  Google Scholar 

  • Chen MF, Hsu HC, Lee YT (1994) Effects of acute exercise on the changes of lipid profiles and peroxides, prostanoids, and platelet activation in hypercholesterolemic patients before and after treatment. Prostaglandins 48:157–174

    CAS  Google Scholar 

  • Chia T, Hsu CY, Chen HL (2008) Oxidative damage of workers in secondary metal recovery plants affected by smoking status and joining the smelting work. Ind Health 46:174–182

    Article  CAS  Google Scholar 

  • Choi HS, Moore DD (1993) Induction of c-fos and c-jun gene expression by phenolic antioxidants. Mol Endocrinol 7:1596–602

    Article  CAS  Google Scholar 

  • Church DF, Pryor WA (1985) Free-radical chemistry of cigarette smoke and its toxicologicalimplications. Environ Health Perspect 64:111–126

    Article  CAS  Google Scholar 

  • Corrao G, Bagnardi V, Zambon A, La Vecchia C (2004) A metaanalysis of alcohol consumption and the risk of 15 diseases. Prev Med 38:613–619

    Article  Google Scholar 

  • Costa D, Guignard J, Pezerat H (1989) Production of free radicals arising from the surface activity of minerals and oxygen. Part II. Arsenites, sulfides, and sulfoarsenites of iron, nickel and copper. Toxicol Ind Health 5:1079–1097

    CAS  Google Scholar 

  • Craig L, Brook JR, Chiotti Q, Croes B, Gower S, Hedley A, Krewski D, Krupnick A, Krzyzanowski M, Moran MD, Pennell W, Samet JM, Schneider J, Shartreed J, Williams M (2008) Air pollution and public health: a guidance document for risk managers. J Toxicol Environ Health A 71:588–698

    Article  CAS  Google Scholar 

  • Damek-Poprawa M, Sawicka-Kapusta K (2004) Histopathological changes in the liver, kidneys, and testes of bank voles environmentally exposed to heavy metal emissions from the steelworks and zinc smelter in Poland. Environ Res 96:72–78

    Article  CAS  Google Scholar 

  • Davison GW, George L, Jackson SK, Young IS, Davies B, Bailey BM, Peters JR, Ashton T (2002) Exercise, free radicals and lipid peroxidation in type 1 diabetes mellitus. Free Radic Biol Med 33:1543–1551

    Article  CAS  Google Scholar 

  • Dietrich M, Block G, Norkus EP, Hudes M, Traber MG, Cross CE, Packer L (2003) Smoking and exposure to environmental tobacco smoke decrease some plasma antioxidants and increase gamma-tocopherol in vivo after adjustment for dietary antioxidant intakes. Am J Clin Nutr 77:160–166

    CAS  Google Scholar 

  • Diffey BL (2002) Source and measurement of ultra violet radiation. Methods 28:4–13

    Article  CAS  Google Scholar 

  • Dourado DF, Fernandes PA, Mannervik B, Ramos MJ (2008) Glutathione transferase: new model for glutathione activation. Chemistry 14:9591–9598

    Article  CAS  Google Scholar 

  • Eisner MD, Balmes J, Katz PP, Trupin L, Yelin EH, Blanc PD (2005) Lifetime environmental tobacco smoke exposure and the risk of chronic obstructive pulmonary disease. Environ Health 4:7–9

    Article  Google Scholar 

  • Elwood JM, Pearson JCG, Skippen DH (1984) Alcohol, smoking, social and occupational factors in the aetiology of cancer of the oral cavity, pharynx and larynx. Int J Cancer 34:603–612

    Article  CAS  Google Scholar 

  • Falcon M, Vinas P, Perez-Carceles MD, Luna A (2003) Placental cadmium and lipid peroxidation in smoking women related to newborn anthropometric measurement. Arch Environ Contam Toxicol 45:278–282

    Article  CAS  Google Scholar 

  • Flora SJS, Flora G, Saxena G (2006) Environmental occurrence, health effects and management of lead poisoning. In: Cascas SB, Sordo J (eds) Lead chemistry, analytical aspects, environmental impacts and health effects. Elsevier Publication, Netherlands, pp 158–228

    Google Scholar 

  • Flora SJS, Mittal M, Mehta A (2008) Heavy metal induced oxidative stress & its possible reversal by chelation therapy. Indian J Med Res 128:501–523

    CAS  Google Scholar 

  • Flora SJS, Pande M, Kannan GM, Mehta A (2004) Lead induced oxidative stress and its recovery following co-administration of melatonin or N-acetylcysteine during chelation with succimer in male rats. Cell Mol Biol 50:543–551

    Google Scholar 

  • Flora SJS, Saxena G, Gautam P, Kaur P, Gill KD (2007) Response of lead-induced oxidative stress and alterations in biogenic amines in different rat brain regions to combined administration of DMSA and MiADMSA. Chem-Biol Interact 170:209–220

    Article  CAS  Google Scholar 

  • Franceschi S, Levi F, La Vecchia C, Conti E, Dal Maso L, Barzan L, Talamini R (1999) Comparison of the effect of smoking and alcohol drinking between oral and pharyngeal cancer. Int J Cancer 83:1–4

    Article  CAS  Google Scholar 

  • Frei B, Forte TM, Ames BN, Cross CE (1991) Gas phase oxidants of cigarette smoke induce lipid peroxidation and changes in lipoprotein properties in human blood plasma. Biochem J 277:133–138

    CAS  Google Scholar 

  • Fuchs J, Weber S, Kaufmann R (2000) Genotoxic potential of porphyrin type photosensitizers with particular emphasis on 5-aminolevulinic acid: implications for clinical photodynamic therapy. Free Radical Biol Med 28:537–548

    Article  CAS  Google Scholar 

  • Galicia-Garcia V, Rojas-Lopez M, Rojas R, Olaiz G, Rios C (1997) Cadmium levels in maternal, cord and newborn blood in Mexico City. Toxicol Lett 91:57–61

    Article  CAS  Google Scholar 

  • Gomez-Cabrera MC, Vina J, Ji LL (2009) Interplay of oxidants and antioxidants during exercise: implications for muscle health. Phys Sports Med 37:116–123

    Article  Google Scholar 

  • Gupta SK, Singhvi IJ (2011) Herbal and hepatoprotective drugs acting on peptic ulcer and liver disease: a review. International Journal of Pharmacy & Technology 3:824–853

    Google Scholar 

  • Hackshaw AK, Law MR, Wald NJ (1997) The accumulated evidence on lung cancer and environmental tobacco smoke. Br Med J 315:980–988

    Article  CAS  Google Scholar 

  • Halliwell B, Gutteridge J (1990) (eds) Free radicals in biology and medicine. Oxford University Press, New York, 105–245

  • Halliwell B, Gutteridge JMC (1989) Free radicals in biology and medicine, 2nd edn. Clarendon, Oxford

    Google Scholar 

  • Harman D (1956) Aging: a theory based on free radical and radiation chemistry. J Gerontol 11:298–300

    Article  CAS  Google Scholar 

  • Hassan MM, Hwang LY, Hatten CJ, Swaim M, Li D, Abbruzzese JL, Beasley P, Patt YZ (2002) Risk factors for hepatocellular carcinoma: synergism of alcohol with viral hepatitis and diabetes mellitus. Hepatology 36:1206–1213

    Article  CAS  Google Scholar 

  • Heidrich J, Wellmann J, Heuschmann PU, Kraywinkel K, Keil U (2007) Mortality and morbidity from coronary heart disease attributable to passive smoking. Eur Heart J 28:2498–2502

    Article  CAS  Google Scholar 

  • Herrling T, Jung K, Fuchs J (2007a) The important role of melanin as protector against free radicals in skin. SOFW 133(9):26–33

    CAS  Google Scholar 

  • Herrling T, Jung K, Fuchs J (2007b) UV-generated free radicals (FR) in skin and hair—their formation, action, elimination and prevention. A general view. SOFW 133:1–11

    Google Scholar 

  • Iwasawa Y, Ogasawara S, Onish T, Tamara K (1974) Dehydrogenation and dehydration of ethyl alcohol over a polynaphthoquinone containing various amounts of FeCl3: selectivity of formation of acetaldehyde, ethylene and diethyl ether. J. Chem. Soc. Faraday Trans I 70:193–201

    Article  CAS  Google Scholar 

  • Jackson MJ (2000) Exercise and oxygen radical production by muscle. In: Sen C, Packer L, Hanninen O (eds) Handbook of oxidants and antioxidants in exercise. Amsterdam, Elsevier Science, pp 57–68

    Google Scholar 

  • Jai Z, Misra HP (2007) Reactive oxygen species in in vitro pesticide-induced neuronal cell (SH-SY5Y) cytotoxicity: Role of NFκB and caspase-3. Free Radic Biol Med 42(2):288–298

    Article  CAS  Google Scholar 

  • Jeyadevi R, Sivasudha T, Rameshkumar A, Harnly JM, Lin IZ (2012) Phenolic profiling by UPLC-MS/MS and hepatoprotective activity of Cardiospermum helicacabum against acetaminophen induced liver injury in wistar rats. Journal Funct Foods. doi:10.1016/j.jff.2012.10.019

    Google Scholar 

  • John Brick (2005) Alcohol poisoning. A publication of Intoxikon international. http://www.intoxikon.com/Pubs/Facts%20on%20ALCOHOL%20POISONING_4_7_05.pdf.

  • Jost M, Gasparro FP, Jensen PJ, Rodeck U (2001) Keratinocyteapoptosis induced by ultraviolet B radiation and CD95 ligation—differential protection through epidermal growth factor receptor activation and Bcl-xL expression. J Investig Dermatol 116:860–866

    Article  CAS  Google Scholar 

  • Jung K, Seifert M, Herrling T, Fuchs J (2008) UV-generated free radicals (FR) in skin: their prevention by sunscreens and their induction by self-tanning agents. Spectrochimica Acta Part 69:1423–1428

    Article  CAS  Google Scholar 

  • Kabe Y, Ando K, Hirao S, Yoshida M, Handa H (2005) Redox regulation of NFkappaB activation: distinct redox regulation between the cytoplasm and the nucleus. Antioxid. Redox Signal 7:395–403

    Article  CAS  Google Scholar 

  • Kaiser J (1998) Toxicologists shed new light on old poisons. Sci 279:1850–1851

    Article  CAS  Google Scholar 

  • Kansal L, Sharma V, Sharma A, Lodi S, Sharma SH (2011) Protective role of Coriandrum sativum (Coriander) extracts against lead nitrate induced oxidative stress and tissue damage in the liver and kidney in male mice. Int J Appl Biol Pharm Technol 2(3):65–83

    Google Scholar 

  • Kato S, Kawase T, Alderman J, Inatori N, Lieber CS (1990) Role of xanthine oxidase in ethanol-induced lipid peroxidation. Gastroenterology 98:203

    CAS  Google Scholar 

  • Kayhanian H (2012) Trend and concentrations of legacy lead (Pb) in highway runoff. Environ Pollut 190:169–177

    Article  CAS  Google Scholar 

  • Khalil-Manesh F, Gonick HC, Weiler EW, Prins B, Weber MA, Purdy RE (1993) Lead-induced hypertension: possible role of endothelial factors. Am J Hypertens 6:723–729

    CAS  Google Scholar 

  • Kim JY, Mukherjee S, Ngo L, Christiani DC (2004) Urinary 8-hydroxy-2-deoxyguanosine as a biomarker of oxidative DNA damage in workers expose to fine particulates. Environ. Health Perspect 112:666–671

    Article  CAS  Google Scholar 

  • Kishore G, Sharma AP, Murthy SDS (2010) Free radical mediated damage in the thylakoid photo function of Barley thylakoid membranes under UV-B radiation: analysis of possible protection mechanism. Am-EurasJSciRes 5:1–4

    CAS  Google Scholar 

  • Landolph JR (1999) Role of free radicals in metal-induced carcinogenesis. Metal Ion Biol Syst 36:445–483

    CAS  Google Scholar 

  • Landry LG, Chapple CC, Last RL (1995) Arabidopsis mutants lacking phenolic sunscreens exhibit enhanced ultraviolet-B injury and oxidative damage. Plant Physiol 109:1159–1166

    Article  CAS  Google Scholar 

  • Lanphear BP, Dietrich K, Auinger P, Cox C (2000) Cognitive deficits associated with blood lead concentrations <10 μg/dl in US children and adolescents. Public Health Rep 115:521–529

    Article  CAS  Google Scholar 

  • Leeuwenburgh C, Hansen PA, Holloszy JO, Heinecke JW (1999) Hydroxyl radical generation during exercise increases mitochondrial protein oxidation and levels of urinary dityrosine. Free Rad Biol Med 27:186–192

    Article  CAS  Google Scholar 

  • Leonard SS, Harris GK, Shi XL (2004) Metal-induced oxidative stress and signal transduction. Free Rad Biol Med 37:1921–42

    Article  CAS  Google Scholar 

  • Lieber CS (1997) Ethanol metabolism, cirrhosis and alcoholism. ClinchimActa 257:59

    Article  CAS  Google Scholar 

  • Lieber CS (2005) Metabolism of alcohol. Clin Liver Dis 9:1–35

    Article  Google Scholar 

  • Long TC, Saleh N, Tilton RD, Lowry G, Veronesi B (2006) Titanium dioxide (P25) produces reactive oxygen species in immortalized brain microglia (BV2): implications for nanoparticle neurotoxicity. Environ. Part Sci Technol 40:4346–4352

    Article  CAS  Google Scholar 

  • Macip S, Igarashi M, Berggren P, Yu J, Lee SW, Aaronson SA (2003) Influence of induced reactive oxygen species in p53-mediated cell fate decisions. Mol. Cell Biol 23:8576–8585

    CAS  Google Scholar 

  • Markus MA, Morris BJ (2008) Resveratrol in prevention and treatment of common clinical conditions of aging. Clin Interv Aging 3:331–339

    CAS  Google Scholar 

  • Marrot L, Jones C, Perez P, Meunier JR (2008) The significance of Nrf2 pathway in (photo)-oxidative stress response in melanocytes and keratinocytes of the human epidermis. Pigment Cell Melanoma Res 21:79–88

    Article  CAS  Google Scholar 

  • Meister A (1988) Glutathione metabolism and its selective modification. J Biol Chem 263:17205–17208

    CAS  Google Scholar 

  • Mohammad Shamssain (2011) Science Daily. July 6. http://www.sciencedaily.com/releases/2011/07/110706094329.ht

  • Mohora M, Greabu M, Totan A, Mitrea N, Battino M (2009) Redox sensitive signaling factors and antioxidants. Farmacia 57(4):399–410

    CAS  Google Scholar 

  • Nadeem M, Shafique R, Yaldram A, López R (2011) Intraoral distribution of oral melanosis and cigarette smoking in a Pakistan population. Int J Dent Clin 3(1):25–28

    Google Scholar 

  • Nemmar A, Inuwa IM (2008) Diesel exhaust particles in blood trigger systemic and pulmonary morphological alterations. Toxicol Lett 176:20–30

    Article  CAS  Google Scholar 

  • Oliveira RJD, Duarte JA, Sanchez-Navarro A, Remiao F, Bastos ML, Carvalho F (2008) Paraquat poisonings: mechanisms of lung toxicity, clinical features, and treatment. Crit Rev Toxicol 8:13–71

    Article  CAS  Google Scholar 

  • Onaran I, Ozaydin A, Gultepe M, Sultuybek G (1998) Transport of glutathione conjugate in erythrocytes from aged subjects and susceptibility to oxidative stress following inhibition of the glutathione S-conjugate pump. Mechanisms of Ageing and Development 103:195–207

    Article  CAS  Google Scholar 

  • Ortega G, Castella C, Martin-Cantera C, Ballve JL, Diaz E, Saez M, Lozano J, Morero R, Barcelo A, Cabezan C, Pascual JA, Perez- ortuno R, Salto E, Valverde A, Jane M (2010) Passive smoking in babies: the BIBE study (Brief Intervention in Babies Effectiveness). BMC Publ Health 10:772–782

    Article  Google Scholar 

  • Paula EM, Mathangi DC, Namasivayam (2003) A free radical changes in methanol toxicity. Indian J Physiol Pharmacol 47(2):207–211

    CAS  Google Scholar 

  • Peraza MA, Ayala-Fierro F, Barber DS, Casarez E, Rael LT (1998) Effects of micronutrients on metal toxicity. Environ Health Perspect 106:203–216

    CAS  Google Scholar 

  • Perkins ND (2007) Integrating cell-signalling pathways with NF-kappaB and IKK function. Nat. Rev. Mol. Cell Biol 8:49–62

    CAS  Google Scholar 

  • Pham-Huy LA, He H, Pham-Huyc C (2008) Free Radicals, Antioxidants in Disease and Health. Int J Biomed Sci 4:89–96

    Google Scholar 

  • Piasek M, Blanusa M, Kostial K, Laskey JW (2001) Placental cadmium and progesterone concentrations in cigarette smokers. Reprod Toxicol 15:673–681

    Article  CAS  Google Scholar 

  • Prasad KN, Hao J, Yi C, Zhang D, Qiu S, Jiang Y, Zhang M, Chen F (2009) Antioxidant and anticancer activities of wampee (Clausena lansium (Lour.) Skeels) peel. J Biomed Biotechnol. doi:10.1155/2009/612805

  • Pryor WA, Stone K, Zang LY, Bermudez E (1998) Fractionation of aqueous cigarette tar extracts: fractions that contain the tar radical cause DNA damage. Chem Res Toxicol 11:441–448

    Article  CAS  Google Scholar 

  • Radak Z, Sasvari M, Nyakas C, Kaneko T, Tahara S, Ohno H, Goto S (2001) Single bout of exercise eliminates the immobilization induced oxidative stress in rat brain. Neurochem Int 39:33–38

    Article  CAS  Google Scholar 

  • Rameshkumar A, Sivasudha T, Jeyadevia R, Sangeetha B, Arul Ananth D, Smilin Bell Aseervatham G, Nagarajan N, Renganathan R, Kathiravan A (2013) In vitro antioxidant and antimicrobial activities of Merremia emarginata using thio glycolic acid-capped cadmium telluride quantum dots. Colloids and Surfaces B: Biointerfaces 101:74–82

    Article  CAS  Google Scholar 

  • Rehm J, Baliunas D, Borges GL, Graham K, Irving H, Kehoe T, Parry CD, Patra J, Popova S, Poznyak V, Roerecke M, Room R, Samokhvalov AV, Taylor B (2010) The relation between different dimensions of alcohol consumption and burden of disease: an overview. Addiction 105:817–843

    Article  Google Scholar 

  • Riedl MA (2008) The effect of air pollution on asthma and allergy. Curr Allergy Asthma Rep 8:139–146

    Article  CAS  Google Scholar 

  • Rodgman A, Smith CJ, Perfetti TA (2000) The composition of cigarette smoke: a retrospective, with emphasis on polycyclic components. Hum Exp Toxicol 19:573–595

    Article  CAS  Google Scholar 

  • Rossner P, Svecovaa V, Milcovaa A, Lnenickovaa Z, Solanskya I, Sram RJ (2008) Seasonal variability of oxidative stress markers in city bus drivers. Part II. Oxidative damage to lipids and proteins. Mutat Res 642:14–20

    Article  CAS  Google Scholar 

  • Sabir SM, Ahmad SD, Hamid A, Khan MQ, Athayde ML et al (2012) Antioxidant and hepatoprotective activity of ethanolic extract of leaves of Solidago microglossa containing polyphenolic compounds. Food Chem 131:741–747

    Article  CAS  Google Scholar 

  • Sachdev S, Davies KJA (2008) Production, detection and adaptive responses to free radicals in exercise. Free Radic Biol Med 44:215–223

    Article  CAS  Google Scholar 

  • Sakurai H, Yasui H, Yamada Y, Nishimura H, Shigemoto M (2005) Detection of reactive oxygen species in the skin of live mice and rats exposed to UVA light: a research review on chemiluminescence and trials for UVA protection. Photochem Photobiol Sci 4:715–720

    Article  CAS  Google Scholar 

  • Santanam N, Sanchez R, Hendler S, Parthasarathy S (1997) Aqueous extracts of cigarette smoke promote the oxidation of low density lipoprotein by peroxidases. FEBS Lett 414:549–551

    Article  CAS  Google Scholar 

  • Sarma AD, Mallick AR, Ghosh AK (2010) Free radicals and their role in different clinical conditions: an overview. Int J Pharma Sci Res 1:185–192

    Google Scholar 

  • Sasikumar JM, Maheshu V, Smilin Bell Aseervatham G, Darshini TP (2010) In vitro antioxidant activity of Hedyotis corymbosa (L.) Lam. aerial parts. Indian J Biochem Biophys 47:49–52

    CAS  Google Scholar 

  • Saxena G, Joshi U, Flora SJS (2005) Monoesters of meso 2,3-dimercaptosuccinic acid in lead mobilization and recovery of lead induced tissue oxidative injury in rats. Toxicology 214:39–56

    Article  CAS  Google Scholar 

  • Sharma RP, Street JC (1980) Public health aspects of toxic heavy metals in animal feeds. J Am Vet Med Assoc 177:149–153

    CAS  Google Scholar 

  • Sherwin ER (1990) In: Branen AL, Davidson PM, Salminen S (eds) Food additives. Marcel Dekker, New York, pp 139–193

    Google Scholar 

  • Shinagawa K, Tokimoto T, Shirane K (1998) Spin trapping of nitric oxide in aqueous solutions of cigarette smoke. Biochem Biophys Res Commun 253:99–103

    Article  CAS  Google Scholar 

  • Shishodia S, Potdar P, Gairola CG, Aggarwal BB (2003) Curcumin (diferuloylmethane) down-regulates cigarette smoke-induced NF-kB activation through inhibition of IkBα kinase in human lung epithelial cells: correlation with suppression of COX-2, MMP-9 and cyclin D1. Carcinogenesis 24:1269–1279

    Article  CAS  Google Scholar 

  • Sigmund DCE, Wille U (2008) Can the night time atmospheric oxidants NO3 · damage aromatic amino acids? Chem Comm 14:2121–2123

    Article  CAS  Google Scholar 

  • Silvestro A, Scopacasa F, Oliva G, De Cristofaro T, Iuliano L, Brevetti G (2002) Vitamin C prevents endothelial dysfunction induced by acute exercise in patients with intermittent claudication. Atherosclerosis 165:277–283

    Article  CAS  Google Scholar 

  • Simkhovich BZ, Kleinman MT, Kloner RA (2008) Air pollution and cardiovascular injury: epidemiology, toxicology, and mechanisms. J Am Coll Cardiol 52:719–726

    Article  CAS  Google Scholar 

  • Sippl W, Jung M (2009) In: Mannhold R, Kubinyi H, Folkersm G (eds) Epigenetic targets in drug discovery: methods and principles in medicinal chemistry. Wiley, Weinheim, 42

    Chapter  Google Scholar 

  • Skrzydlewska E, Farbiszewski R (1995) Interakcje Wolnych Rodnikow z bialkami. Post Hig Med Dosw 49:747–766

    CAS  Google Scholar 

  • Smilin Bell Aseervatham G, Sasikumar JM, Kumar D (2012a) Studies on in vitro free radical scavenging activity of Bixa orellna L. bark extract. Int J Pharm Pharm Sci 4:719–726

    Google Scholar 

  • Smilin Bell Aseervatham G, Shamna R, Sangeetha B, Sasikumar JM (2012) In vivo antioxidant activity of bark extract of Bixa orellana L. against acetaminophen induced- oxidative stress. Asian Pac J Trop Biomed S700 - S705

  • Somogyi A, Rosta K, Pusztai P, Tulassay Z, Nagy G (2007) Antioxidant measurements. Physiol Meas 28:R41–R55

    Article  Google Scholar 

  • Stoclet JC, Chataigneau T, Ndiaye M, Oak M, Bedoui JE, Chataigneau M, Valerie BS (2004) Vascular protection by dietary polyphenols. Eur J Pharmacol 500(1–3):299–313

    Article  CAS  Google Scholar 

  • Stohs SJ, Bagchi D (1995) Oxidative mechanisms in the toxicity of metal-ions. Free Rad Biol Med 18:321–336

    Article  CAS  Google Scholar 

  • Talamini R, Polesel J, Gallus S, Dal Maso L, Zucchetto A, Negri E, Bosetti C, Lucenteforte E, Boz G, Franceschi S, Serraino D, La Vecchia C (2010) Tobacco smoking, alcohol consumption and pancreatic cancer risk: a case–control study in Italy. Eur J Cancer 46:370–376

    Article  CAS  Google Scholar 

  • Tashkin DP (2005) Smoked marijuana as a cause of lung injury. Monaldi Arch Chest Dis 63:93–100

    CAS  Google Scholar 

  • Temel I, Ozerol E, Bay A, Cigli A, Akyol O (2002) Erythrocyte catalase activities in alcohol consumption, medications and some diseases. Inönü Üniversitesi Tip Fakültesi Dergisi 9:11–14

    Google Scholar 

  • Tephly TR (1991) The toxicity of methanol. Life Sci 48:1031–1041

    Article  CAS  Google Scholar 

  • Thamotharan G, Sekar G, Ganesh T, Sen S, Chakraborty R, Senthil Kumar N (2010) Anti- ulcerogenic effects of Lantana camara Linn. leaves on in vivo test models in rats. Asian J Pharm clin Res 3:57–60

    Google Scholar 

  • Urso ML, Clarkson PM (2003) Oxidative stress, exercise, and antioxidant supplementation. Toxicology 189:41–54

    Article  CAS  Google Scholar 

  • Valko M, Morris H, Cronin MTD (2005) Metals, toxicity and oxidative stress. Curr Med Chem 12:1161–1208

    Article  CAS  Google Scholar 

  • Videla LA (2009) Oxidative stress signaling underlying liver diseases and hepatoprotective mechanism. World J Hepatol 31(1):72–78

    Article  Google Scholar 

  • Vincent HK, Vincent KR, Bourguignon C, Braith RW (2005) Obesity and post exercise oxidative stress in older women. Med Sci Sports Exerc 37:213–219

    Article  CAS  Google Scholar 

  • Vollaard NB, Shearman JP, Cooper CE (2005) Exercise-induced oxidative stress: myths, realities and physiological relevance. Sports Med 35:1045–1062

    Article  Google Scholar 

  • Ward NI, Watson R, Bryce-Smith D (1987) Placenta element levels in relation to fetal development for obstetrically “normal” births: a study of 37 elements. Int J Biosoc Res 9:63–81

    Google Scholar 

  • Wichi HP (1988) Enhanced tumor development by butylated hydroxyanisole (BHA) from the perspective of effect on fore stomach and oesophageal squamous epithelium. Food Chem Toxicol 26:717–723

    Article  Google Scholar 

  • World Cancer Research Fund (2010) Food, nutrition, physical activity, and prevention of cancer: a global perspective. AICR, Washington, DC

    Google Scholar 

  • Yang J, Wang L, Chen Z, Shen ZQ, Jin M, Wang XW, Zheng Y, Qiu ZG, Wang JF, Li JW (2008) Antioxidant intervention of smoking-induced lung tumor in mice by vitamin E and quercetin. BMC Cancer 8:383

    Google Scholar 

  • Ye F, Xu XC (2010) Benzo[a]pyrene diol expoide suppresses retinoic acid receptor-β expression by recruiting DNA (cystesine-5-)-methyltransferase 3A. Molecular Cancer 9:1–7

    Article  CAS  Google Scholar 

  • Yedjou C, Izevbigie E, Tchounwou P (2008) Preclinical assessment of Vernonia amygdalina leaf extract as DNA damaging anti-cancer agents in the management of breast cancer. IRERPH 5:337–341

    Google Scholar 

  • Yildirim A, Oktay MN, Bülaloúlu V (2001) The antioxidant activity of the leaves of Cydonia vulgaris. Turk J Med Sci 31:23–27

    Google Scholar 

  • Yong HY, Cullen AP, Chou BR, Sivak JG (2010) Phototoxicity of ultraviolet (UV) radiation: evaluation of UV-blocking efficiency of intracellular & in vitro bioassay. The Open Toxicology Journal 4:13–20

    Article  CAS  Google Scholar 

  • Yoshioka N, Nakashima H, Hosoda K, Eitaki Y, Shimada N, Omae K (2008) Urinary excretion of an oxidative stress marker, 8-hydroxyguanine (8-OH-Gua), among nickel–cadmium battery workers. J Occup Health 50:229–235

    Article  CAS  Google Scholar 

  • Zhang ZF, Yu SZ, Zhou GD (1988) Indoor air pollution of coal fumes as a risk factor of stroke. Shanghai Am J Public Health 78:975–977

    Article  CAS  Google Scholar 

  • Zhao Y, Wang L, Shen HB, Wang ZX, Wei QY, Chen F (2007) Association between delta-aminolevulinic acid dehydratase (ALAD) polymorphism and blood lead levels: a metaregression analysis. J Toxicol Environ Health A 70:1986–94

    Article  CAS  Google Scholar 

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Acknowledgments

We thank the Department of Environmental Biotechnology, Bharathidasan University, for their support and motivation.

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Authors and Affiliations

  1. Department of Environmental Biotechnology, Bharathidasan University, Tiruchirappalli, 620 024, Tamilnadu, India

    G. Smilin Bell Aseervatham, T. Sivasudha, R. Jeyadevi & D. Arul Ananth

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  1. G. Smilin Bell Aseervatham
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  2. T. Sivasudha
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  3. R. Jeyadevi
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  4. D. Arul Ananth
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Correspondence to T. Sivasudha.

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Aseervatham, G.S.B., Sivasudha, T., Jeyadevi, R. et al. Environmental factors and unhealthy lifestyle influence oxidative stress in humans—an overview. Environ Sci Pollut Res 20, 4356–4369 (2013). https://doi.org/10.1007/s11356-013-1748-0

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