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Pre-activated anti-viral innate immunity in the upper airways controls early SARS-CoV-2 infection in children

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Version 2 2021-07-26, 14:59
Version 1 2021-07-26, 11:44
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posted on 2021-07-26, 14:59 authored by Jennifer Loske, Jobst F. Roehmel, Soeren LukassenSoeren Lukassen, Sebastian Stricker, Vladimir Gonçalves Magalhães, Johannes Liebig, Robert Lorenz Chua, Loreen Thürmann, Marey Messingschlager, Anke Seegebarth, Bernd Timmermann, Sven Klages, Markus Ralser, Birgit Sawitzki, Leif-Erik Sander, Victor M. Corman, Christian ConradChristian Conrad, Sven Laudi, Marco Binder, Saskia Trump, Roland EilsRoland Eils, Marcus Mall, Irina Lehmann
This dataset comprises single-cell RNA-Seq data of nasopharyngeal samples of of adults and children with COVID-19 (n=24 and n=21, respectively) and SARS-CoV-2-negative controls in each age group (n=23 and 18, respectively).
An in-depth description is presented in the manuscript "Pre-activated anti-viral innate immunity in the upper airways controls early SARS-CoV-2 infection in children" (https://www.medrxiv.org/content/10.1101/2021.06.24.21259087v1).

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