Incidence and clinical relevance of primary congenital anomalies of the coronary arteries in children and adults

Cardiol Young. 2013 Jun;23(3):381-6. doi: 10.1017/S1047951112000959. Epub 2012 Jul 20.

Abstract

Objectives: To describe our experience in the management of coronary artery anomalies both in an adult and in a paediatric population and to compare the two groups for finding out differences in terms of angiographic incidence and treatment.

Patients and methods: Databases at the Department of Cardiology of San Martino Adult's Hospital and of Gaslini Children's Hospital were searched for all patients with a diagnosis of coronary artery anomaly who underwent coronary angiography between 1994 and 2006.

Results: Coronary anomalies were diagnosed in 76 (1%) adult patients. Anomalous left circumflex artery was the commonest coronary anomaly (25%). Anomalous left coronary artery from pulmonary artery and myocardial bridges were the only anomalies responsible for angina-like symptoms. No patients except the one with anomalous left coronary artery from pulmonary artery needed surgical intervention. In the paediatric population, we found 28 (0.9%) patients with coronary anomalies. Anomalous left coronary artery from pulmonary artery was the most common anomaly (48%) and always required emergency surgical treatment; in addition there were two patients with stenosis of the left main coronary artery.

Conclusion: Coronary artery anomalies may be associated with very acute, even life-threatening symptoms in children, whereas they are usually clinically silent and detected by accident on coronary angiography in adults. Recognition of coronary artery anomalies enables early treatment or close follow-up in children, whereas it could be useful in case of cardiac surgery in adults.

MeSH terms

  • Adolescent
  • Cardiac Surgical Procedures
  • Child
  • Child, Preschool
  • Coronary Angiography
  • Coronary Vessel Anomalies / diagnosis
  • Coronary Vessel Anomalies / epidemiology*
  • Coronary Vessel Anomalies / therapy
  • Echocardiography
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Italy / epidemiology
  • Middle Aged