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Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults.
Killingley B, Mann AJ, Kalinova M, Boyers A, Goonawardane N, Zhou J, Lindsell K, Hare SS, Brown J, Frise R, Smith E, Hopkins C, Noulin N, Löndt B, Wilkinson T, Harden S, McShane H, Baillet M, Gilbert A, Jacobs M, Charman C, Mande P, Nguyen-Van-Tam JS, Semple MG, Read RC, Ferguson NM, Openshaw PJ, Rapeport G, Barclay WS, Catchpole AP, Chiu C. Killingley B, et al. Among authors: mann aj. Nat Med. 2022 May;28(5):1031-1041. doi: 10.1038/s41591-022-01780-9. Epub 2022 Mar 31. Nat Med. 2022. PMID: 35361992 Clinical Trial.
Viral emissions into the air and environment after SARS-CoV-2 human challenge: a phase 1, open label, first-in-human study.
Zhou J, Singanayagam A, Goonawardane N, Moshe M, Sweeney FP, Sukhova K, Killingley B, Kalinova M, Mann AJ, Catchpole AP, Barer MR, Ferguson NM, Chiu C, Barclay WS. Zhou J, et al. Among authors: mann aj. Lancet Microbe. 2023 Aug;4(8):e579-e590. doi: 10.1016/S2666-5247(23)00101-5. Epub 2023 Jun 9. Lancet Microbe. 2023. PMID: 37307844 Free PMC article. Clinical Trial.
Intranasal H5N1 vaccines, adjuvanted with chitosan derivatives, protect ferrets against highly pathogenic influenza intranasal and intratracheal challenge.
Mann AJ, Noulin N, Catchpole A, Stittelaar KJ, de Waal L, Veldhuis Kroeze EJ, Hinchcliffe M, Smith A, Montomoli E, Piccirella S, Osterhaus AD, Knight A, Oxford JS, Lapini G, Cox R, Lambkin-Williams R. Mann AJ, et al. PLoS One. 2014 May 21;9(5):e93761. doi: 10.1371/journal.pone.0093761. eCollection 2014. PLoS One. 2014. PMID: 24850536 Free PMC article.
A new intranasal influenza vaccine based on a novel polycationic lipid-ceramide carbamoyl-spermine (CCS). II. Studies in mice and ferrets and mechanism of adjuvanticity.
Even-Or O, Joseph A, Itskovitz-Cooper N, Samira S, Rochlin E, Eliyahu H, Goldwaser I, Balasingam S, Mann AJ, Lambkin-Williams R, Kedar E, Barenholz Y. Even-Or O, et al. Among authors: mann aj. Vaccine. 2011 Mar 16;29(13):2474-86. doi: 10.1016/j.vaccine.2011.01.009. Epub 2011 Jan 18. Vaccine. 2011. PMID: 21251901