Molecular Cell
Volume 38, Issue 1, 9 April 2010, Pages 67-77
Article
A Splicing-Independent Function of SF2/ASF in MicroRNA Processing
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Highlights
► Mature miR-7 is upregulated by ectopic expression of splicing factor SF2/ASF ► Reciprocal targeting between SF2/ASF and miR-7 to form a negative feedback circuit ► A splicing-independent function of SF2/ASF in pri-miR-7 maturation ► SF2/ASF directly binds to primary miRNA transcripts and promotes Drosha cleavage
RNA
PROTEINS
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