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Pharmacology of Opiates

  • Chapter
Handbook of Substance Abuse

Abstract

There are three major opioid receptors in the central nervous system: mu, kappa, and delta, the genes for which have been cloned. There are also possible subtypes within each class, although separate genes have not yet been cloned for any subtypes. Opioids are both the natural opiates and their synthetic congeners which are the class of agonist and antagonist drugs with primarily morphine-like activity mostly at the mu opioid receptor, and also the other naturally occurring endogenous and synthetic opioid peptides, which act also at the other receptor types.

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Authors and Affiliations

  1. Laboratory on the Biology of Addictive Diseases, The Rockefeller University, New York, New York, 10021, USA

    Lisa Borg & Mary Jeanne Kreek

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  1. Lisa Borg
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  2. Mary Jeanne Kreek
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Editors and Affiliations

  1. University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA

    Ralph E. Tarter  & Peggy J. Ott  & 

  2. Allegheny University of the Health Sciences, Pittsburgh, Pennsylvania, USA

    Robert T. Ammerman

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Borg, L., Kreek, M.J. (1998). Pharmacology of Opiates. In: Tarter, R.E., Ammerman, R.T., Ott, P.J. (eds) Handbook of Substance Abuse. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-2913-9_23

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