A spokesman for Oprah Winfrey's Harpo Productions says that the talk show queen will announce on today's "The Oprah Winfrey Show" that she will end her daily program.
"Oprah will be ending her talk show," Harpo spokesman Don Halcombe said on Thursday. "She will be speaking about it on tomorrow's live show."
"The Oprah Winfrey Show" will end on September 9, 2011, as its 25th season draws to a close, reports CNN.
For 23 seasons, Winfrey's show has been the highest-rated talk show and seen by roughly 42 million viewers a week in the United States and is broadcast to 145 countries.
In 2008, the showbiz magnate announced that beginning in 2009, the Discovery Health Channel would be named OWN: The Oprah Winfrey Network. The network is "a multi-platform media company designed to entertain, inform and inspire people to live their best lives," according to Oprah.com. Harpo Productions has also grown to include Harpo Films.
Speculators believe that Winfrey will move her show to her cable network.
OWN will be available in more than 70 million homes. The 55 year0\-old talk show host was No. 45 on Forbes magazine's list of the world's most powerful people.