Abstract
The aims of this study were to test the hypothesis that flossing after brushing with a fluoridated toothpaste may lower salivary fluoride (F), and to evaluate the consequence of subsequent F mouthwash use. Twenty adults used 3 oral hygiene regimes in a randomised order: A, brushing with an NaF toothpaste; B, as A but followed by professional flossing; C, as B followed by rinsing with an NaF mouthwash. Saliva samples were collected up to 120 min after each regime and analysed for F. The mean area under the clearance curve value for regime C was statistically significantly greater than the corresponding values for A and B (p < 0.0001), which differed little. The regime that included the mouthwash may provide better anticaries protection.
Publication types
- Randomized Controlled Trial
- Research Support, Non-U.S. Gov't
MeSH terms
- Adolescent
- Adult
- Area Under Curve
- Biological Availability
- Cariostatic Agents / administration & dosage
- Cariostatic Agents / chemistry
- Cariostatic Agents / pharmacokinetics*
- Cross-Over Studies
- Dental Devices, Home Care
- Dentifrices* / chemistry
- Drug Delivery Systems
- Fluorides, Topical / administration & dosage
- Fluorides, Topical / chemistry
- Fluorides, Topical / pharmacokinetics*
- Humans
- Middle Aged
- Mouthwashes* / chemistry
- Oral Hygiene / instrumentation
- Oral Hygiene / methods
- Reference Values
- Saliva / chemistry
- Saliva / metabolism*
- Single-Blind Method
- Therapeutic Irrigation
- Toothbrushing
- Young Adult
Substances
- Cariostatic Agents
- Dentifrices
- Fluorides, Topical
- Mouthwashes