Abstract
We present a previously healthy 6-month-old boy who was admitted to our hospital with lethargy, hypotonia and focal clonic seizures 6 days following diptheria, tetanus toxoid and whole-cell pertussis vaccination. A diagnosis of acute necrotising encephalopathy was made with the aid of MRI, including diffusion-weighted imaging and proton MR spectroscopy.
MeSH terms
- Brain / drug effects
- Brain / pathology*
- Diffusion Magnetic Resonance Imaging / methods*
- Diphtheria / complications*
- Humans
- Infant
- Leukoencephalitis, Acute Hemorrhagic / chemically induced*
- Leukoencephalitis, Acute Hemorrhagic / diagnosis*
- Magnetic Resonance Spectroscopy / methods*
- Male
- Pertussis Vaccine / adverse effects*
- Tetanus Toxin
- Tetanus Toxoid / adverse effects*
Substances
- Pertussis Vaccine
- Tetanus Toxin
- Tetanus Toxoid