Abstract
We conducted a survey on the presence of RotaTeq vaccine viruses in infants hospitalized with respiratory infection, and detected shedding in 17% of children (<2 years of age) who had ever received the vaccine. The latest detection was at the age of 8 months. We conclude that asymptomatic long-time shedding of RotaTeq viruses is not uncommon, and is particularly associated with genotype G1.
MeSH terms
- Antigens, Viral / genetics
- Antigens, Viral / immunology
- Capsid Proteins / genetics
- Capsid Proteins / immunology
- Female
- Genotype
- Humans
- Infant
- Male
- Prospective Studies
- Rotavirus / genetics*
- Rotavirus / immunology*
- Rotavirus Infections / prevention & control*
- Rotavirus Vaccines / administration & dosage
- Rotavirus Vaccines / immunology*
- Vaccination*
Substances
- Antigens, Viral
- Capsid Proteins
- Rotavirus Vaccines
- VP6 protein, Rotavirus