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Auditory and vestibular functions after single or combined exposure to toluene: a review

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Abstract

Toluene is a widely used organic solvent, heavily employed in many manufacturing industries. Recently, evidence has begun to accumulate on the deleterious effect of toluene exposure has on the auditory and vestibular systems. Although little published information exists regarding these effects, the reported findings indicate a need for further investigation. The results of such investigations may dramatically affect occupational hearing conservation practices and legislation. Both human and animal studies will be summarized in discussing the effects of toluene alone or in combination with noise or other chemicals. Gaps in scientific knowledge are highlighted to assist future research.

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Authors and Affiliations

  1. Division of Biomedical and Behavioral Science, National Institute for Occupational Safety and Health, 45226-1998, Cincinnati, Ohio, USA

    Thais C. Morata & Derek E. Dunn

  2. Division of Neuromedicine, National Institute of Occupational Health, S-171 84, Stockholm, Sweden

    Per Nylén & Ann -Christin Johnson

  3. Department of Physiology and Pharmacology, Karolinska Institutet, S-171 77, Stockholm, Sweden

    Per Nylén & Ann -Christin Johnson

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  1. Thais C. Morata
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  2. Per Nylén
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  4. Derek E. Dunn
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Morata, T.C., Nylén, P., Johnson, A.C. et al. Auditory and vestibular functions after single or combined exposure to toluene: a review. Arch Toxicol 69, 431–443 (1995). https://doi.org/10.1007/s002040050196

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