Skip to main content

Suppressive Effect of ERW on Lipid Peroxidation and Plasma Triglyceride Level

  • Conference paper
  • First Online:
Book cover Animal Cell Technology: Basic & Applied Aspects

Abstract

Electrolyzed reduced water (ERW) containing hydrogen molecules and Pt nanoparticles is expected as a new antioxidant. Thiobarbituric acid reactive substances (TBARS) assay revealed that ERW had an inhibitory effect on the oxidation of low-density lipoproteins (LDL). In addition, ERW significantly suppressed LDL oxidation in the medium cultured J.774.A1 macrophage like cells. ERW inhibited Cu2+ ion-catalyzed oxidation of LDL ex vivo. ERW lowered lipid peroxide level in blood red cells and plasma triglyceride in rats fed a basal diet containing 2% cholesterol. These results suggest that ERW has anti-LDL oxidation and anti-hyperlipidemia effects.

Keywords

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 259.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 329.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Ye J., Li Y.-P., Hamsaki T., Nakamichi N., Komatsu T., Kashiwagi T., Teruya K., Nishikawa R., Kawahara T., Osada K., Toh K., Abe M., Tian H., Kabayama S., Otsubo K., Morisawa S., Katakura Y., and Shirahata S. (2008) Inhibitory effect of electrolyzed reduced water on tumor angiogenesis. Biol. Pharm. Bull. 31: 19–26.

    Article  CAS  PubMed  Google Scholar 

  2. Ihm S.H., Yoo H.J., Park S.W., and Ihm J. (1999) Effect of aminoguanidine on lipid peroxidation in streptozotocin-induced diabetic rats. Metabolism 48: 1141–1145.

    Google Scholar 

  3. Yagi K. (1976) A simple fluorometric assay for lipoprotein in blood plasma. Biochem Med. 15: 212–216.

    Article  CAS  PubMed  Google Scholar 

  4. Ohkawa H., Ohishi N., and Yagi K. (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem. 95: 351–358.

    Article  CAS  PubMed  Google Scholar 

  5. Iwai K., Nakaya N., Kawasaki Y., and Matsue H. (2002) The inhibitory effect of natto, a kind of fermented soybeans, on LDL oxidation in vitro. J. Agric. Food Chem. 50: 3592–3596.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sanetaka Shirahata .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2010 Springer Science+Business Media B.V.

About this paper

Cite this paper

Abe, M. et al. (2010). Suppressive Effect of ERW on Lipid Peroxidation and Plasma Triglyceride Level. In: Kamihira, M., Katakura, Y., Ito, A. (eds) Animal Cell Technology: Basic & Applied Aspects. Animal Cell Technology: Basic & Applied Aspects, vol 16. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-3892-0_52

Download citation

Publish with us

Policies and ethics