The IUPHAR/BPS Guide to PHARMACOLOGY

The IUPHAR/BPS Guide to PHARMACOLOGY (GtoPdb), created in a collaboration between The British Pharmacological Society (BPS) and the International Union of Basic and Clinical Pharmacology (IUPHAR), aims to be a “one-stop shop” source of quantitative information on drug targets and the prescription medicines and experimental drugs that act on them. We hope that the Guide to Pharmacology will be useful for researchers and students in pharmacology and drug discovery and provide the general public with accurate information on the basic science underlying drug action. The current version of the database contains: - Succinct overviews of the key properties and recommended ligands of over 2,800 established or potential pharmacological targets, organised by family or group of related targets; - Over 8,800 small molecule, peptide and antibody experimental compounds and approved drugs; - Over 15,000 curated interactions and binding constants between ligands and targets. This information was originally based on data published in the 5th (2011) edition of the BPS Guide to Receptors and Channels (GRAC), now updated in the 2015/16 Concise Guide to Pharmacology (http://www.guidetopharmacology.org/concise) with new information and targets. More detailed information is provided for a subset of important targets, many of which were contained in the original IUPHAR database. These detailed view pages provide in-depth coverage of the properties and ligands of G protein-coupled receptors (GPCRs), ion channels, nuclear receptors and kinases, curated and peer-reviewed by a network of 800 experts. The original IUPHAR-DB site is no longer being developed and all content from that site is now included in the Guide to PHARMACOLOGY. The Guide to PHARMACOLOGY team can be contacted via the email address enquiries <at> guidetopharmacology <dot> org

Website

https://www.guidetopharmacology.org/

External link for The IUPHAR/BPS Guide to PHARMACOLOGY

Industry

Data Infrastructure and Analytics

Company size

2-10 employees

Headquarters

Edinburgh, Midlothian

Type

Nonprofit

Founded

2011

Specialties

Pharmacology, Data curation, Biocuration, and Chemical curation