Collective evolution and the genetic code

Proc Natl Acad Sci U S A. 2006 Jul 11;103(28):10696-701. doi: 10.1073/pnas.0603780103. Epub 2006 Jul 3.

Abstract

A dynamical theory for the evolution of the genetic code is presented, which accounts for its universality and optimality. The central concept is that a variety of collective, but non-Darwinian, mechanisms likely to be present in early communal life generically lead to refinement and selection of innovation-sharing protocols, such as the genetic code. Our proposal is illustrated by using a simplified computer model and placed within the context of a sequence of transitions that early life may have made, before the emergence of vertical descent.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Evolution, Molecular*
  • Gene Transfer, Horizontal*
  • Genetic Code*
  • Models, Genetic*
  • Multigene Family