Immunological time scale for hominid evolution

Science. 1967 Dec 1;158(3805):1200-3. doi: 10.1126/science.158.3805.1200.

Abstract

Several workers have observed that there is an extremely close immunological resemblance between the serum albumins of apes and man. Our studies with the quantitative micro-complement fixation method confirm this observation. To explain the closeness of the resemblance, previous workers suggested that there has been a slowing down of albumin evolution since the time of divergence of apes and man. Recent evidence, however, indicates that the albumin molecule has evolved at a steady rate. Hence, we suggest that apes and man have a more recent common ancestry than is usually supposed. Our calculations lead to the suggestion that, if man and Old World monkeys last shared a common ancestor 30 million years ago, then man and African apes shared a common ancestor 5 million years ago, that is, in the Pliocene era.

MeSH terms

  • Animals
  • Biological Evolution*
  • Haplorhini
  • Hominidae*
  • Humans
  • Immunochemistry
  • Molecular Biology
  • Serum Albumin*

Substances

  • Serum Albumin