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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 4
2003 4
2004 7
2005 3
2006 2
2007 5
2008 3
2009 1
2010 6
2011 3
2012 7
2013 14
2014 15
2015 8
2016 12
2017 5
2018 3
2019 3
2020 4
2021 3
2022 2
2024 0

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106 results

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Page 1
Discovery of GDC-0077 (Inavolisib), a Highly Selective Inhibitor and Degrader of Mutant PI3Kα.
Hanan EJ, Braun MG, Heald RA, MacLeod C, Chan C, Clausen S, Edgar KA, Eigenbrot C, Elliott R, Endres N, Friedman LS, Gogol E, Gu XH, Thibodeau RH, Jackson PS, Kiefer JR, Knight JD, Nannini M, Narukulla R, Pace A, Pang J, Purkey HE, Salphati L, Sampath D, Schmidt S, Sideris S, Song K, Sujatha-Bhaskar S, Ultsch M, Wallweber H, Xin J, Yeap S, Young A, Zhong Y, Staben ST. Hanan EJ, et al. Among authors: eigenbrot c. J Med Chem. 2022 Dec 22;65(24):16589-16621. doi: 10.1021/acs.jmedchem.2c01422. Epub 2022 Dec 1. J Med Chem. 2022. PMID: 36455032
Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity.
Dendrou CA, Cortes A, Shipman L, Evans HG, Attfield KE, Jostins L, Barber T, Kaur G, Kuttikkatte SB, Leach OA, Desel C, Faergeman SL, Cheeseman J, Neville MJ, Sawcer S, Compston A, Johnson AR, Everett C, Bell JI, Karpe F, Ultsch M, Eigenbrot C, McVean G, Fugger L. Dendrou CA, et al. Among authors: eigenbrot c. Sci Transl Med. 2016 Nov 2;8(363):363ra149. doi: 10.1126/scitranslmed.aag1974. Sci Transl Med. 2016. PMID: 27807284 Free PMC article.
Two-in-One antibodies with dual action Fabs.
Eigenbrot C, Fuh G. Eigenbrot C, et al. Curr Opin Chem Biol. 2013 Jun;17(3):400-5. doi: 10.1016/j.cbpa.2013.04.015. Epub 2013 May 14. Curr Opin Chem Biol. 2013. PMID: 23683347 Review.
Design of Organo-Peptides As Bipartite PCSK9 Antagonists.
Burdick DJ, Skelton NJ, Ultsch M, Beresini MH, Eigenbrot C, Li W, Zhang Y, Nguyen H, Kong-Beltran M, Quinn JG, Kirchhofer D. Burdick DJ, et al. Among authors: eigenbrot c. ACS Chem Biol. 2020 Feb 21;15(2):425-436. doi: 10.1021/acschembio.9b00899. Epub 2020 Jan 30. ACS Chem Biol. 2020. PMID: 31962046
A trigger squeezed.
Eigenbrot C. Eigenbrot C. Structure. 2008 Mar;16(3):332-4. doi: 10.1016/j.str.2008.02.002. Structure. 2008. PMID: 18334205 Free article. No abstract available.
Structure-based optimization of hydroxylactam as potent, cell-active inhibitors of lactate dehydrogenase.
Wei B, Robarge K, Labadie SS, Chen J, Corson LB, DiPasquale A, Dragovich PS, Eigenbrot C, Evangelista M, Fauber BP, Hitz A, Hong R, Lai KW, Liu W, Ma S, Malek S, O'Brien T, Pang J, Peterson D, Salphati L, Sampath D, Sideris S, Ultsch M, Xu Z, Yen I, Yu D, Yue Q, Zhou A, Purkey HE. Wei B, et al. Among authors: eigenbrot c. Bioorg Med Chem Lett. 2022 Mar 1;59:128576. doi: 10.1016/j.bmcl.2022.128576. Epub 2022 Jan 19. Bioorg Med Chem Lett. 2022. PMID: 35065235
106 results