Parent Class:

EC-Numbers → 1 -- Oxidoreductases → 1.1 -- Acting on the CH-OH group of donors → 1.1.1 -- With NAD(+) or NADP(+) as acceptor

Synonyms: 21-hydroxysteroid dehydrogenase (NAD)

Systematic Name: 21-hydroxysteroid:NAD⁺ 21-oxidoreductase

Unification Links: BRENDA:1.1.1.150, ENZYME:1.1.1.150, IUBMB-ExplorEnz:1.1.1.150

Reaction:
pregnan-21-ol + NAD⁺ = pregnan-21-al + NADH + H⁺

Summary:
Acts on a number of 21-hydroxycorticosteroids.

Citations: [Monder65]

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References

Monder65: Monder C, White A (1965). "The 21-hydroxysteroid dehydrogenases of liver. A nicotinamide adenine dinucleotide phosphate dehydrogenase and two nicotinamide adenine dinucleotide dehydrogenases." J Biol Chem 240;71-7. PMID: 14253469

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 46(D1):D633-D639 2018
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