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The Diagnosis of COVID ARF in Elderly: The Radiological Findings in Elderly

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Covid-19 Airway Management and Ventilation Strategy for Critically Ill Older Patients

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Abstract

The world aging population is continuously rising, and older age even in Italy is an important risk for COVID-19 infection and mortality. Lung aging is accompanied by physiological functional and morphologic-structural changes that lead to increased respiratory impairment in the elderly. Increased vulnerability of elderly patients with chronic comorbidities and weaker immune function makes them an easier target of viral infection and acute respiratory failure. The COVID-19 pandemic poses a high risk to older people.

Thoracic imaging plays a pivotal role for the diagnosis, temporal evolution, complications, monitoring of therapeutic efficacy, and elderly COVID-19 patients discharge assessment. The aim of this chapter is to provide a rapid overview of the COVID-19 disease imaging, with a specific focus on older adults.

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References

  1. Zhu N, Zhang D, Wang WJ, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382:727–33. https://doi.org/10.1056/NEJMoa2001017.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Ensor RE, Fleg JL, Kim YC, de Leon EF, Goldman SM. Longitudinal chest x-ray changes in normal men. J Gerontol. 1983;38:307–14.

    Article  CAS  PubMed  Google Scholar 

  3. Copley SJ, Wells AU, Hawtin KE, Gibson DJ, Hodson JM, Jacques AET, Hansell DM. Lung morphology in the elderly: comparative CT study of subjects over 75 years old versus those under 55 years old. Radiology. 2009;251:566–73. https://doi.org/10.1148/radiol.2512081242.

    Article  PubMed  Google Scholar 

  4. Schröder TH, Storbeck B, Rabe KF, Weber C. The aging lung: clinical and imaging findings and the fringe of physiological state. RöFo. 2015;187:430–9. https://doi.org/10.1055/s-0034-1399227.

    Article  PubMed  Google Scholar 

  5. Winter DH, Manzini M, Salge JM, Busse A, Jaluul O, Filho WJ, Mathias W, Terra-Filho M. Aging of the lungs in asymptomatic lifelong nonsmokers: findings on HRCT. Lung. 2015;193:283–90. https://doi.org/10.1007/s00408-015-9700-3.

    Article  PubMed  Google Scholar 

  6. Copley SJ. Morphology of the aging lung on computed tomography. J Thorac Imaging. 2016;31:140–50. https://doi.org/10.1097/RTI.0000000000000211.

    Article  PubMed  Google Scholar 

  7. Cheng Y, Luo R, Wang K, et al. Kidney disease is associated with in-hospital death of patients with COVID-19. Kidney Int. 2020;97(5):829–38.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Guan WJ, Ni ZY, Hu Y, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020;382:1708–20. https://doi.org/10.1056/NEJMoa2002032.

    Article  CAS  PubMed  Google Scholar 

  9. Wong HYF, Lam HYS, Fong AH, Leung ST, Chin TW, Lo CSY, Lui MM, Lee JCY, Chiu KW, Chung T, Lee EYP, Wan EYF, Hung FNI, Lam TPW, Kuo M, Ng MY. Frequency and distribution of chest radiographic findings in COVID-19 positive patients. Radiology. 2019;2:201160. https://doi.org/10.1148/radiol.2020201160.

    Article  Google Scholar 

  10. Rodrigues JCL, Hareb SS, Edeyc A, Devarajd A, Jacobe J, Johnstoneg A, McStayh R, Nairi A, Robinson G. An update on COVID-19 for the radiologist—a British society of thoracic imaging statement. Clin Radiol. 2020;75:323–5. https://doi.org/10.1016/j.crad.2020.03.003.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Valente T, Lassandro F, Marino M, Squillante F, Aliperta M, Muto R. H1N1 pneumonia: our experience in 50 patients with a severe clinical course of novel swine-origin influenza a (H1N1) virus (S-OIV). Radiol Med. 2012;117:165–84. https://doi.org/10.1007/s11547-011-0734-1.

    Article  CAS  PubMed  Google Scholar 

  12. Mongodi S, Pozzi M, Orlando A, et al. Lung ultrasound for daily monitoring of ARDS patients on extracorporeal membrane oxygenation: preliminary experience. Intensive Care Med. 2018;44:123–4. https://doi.org/10.1007/s00134-017-4941-7.

    Article  PubMed  Google Scholar 

  13. Patel CJ, Bhatt HB, Parikh SN, Jhaveri BN, Puranik JH. Bedside lung ultrasound in emergency protocol as a diagnostic tool in patients of acute respiratory distress presenting to emergency department. J Emerg Trauma Shock. 2018;11(2):125–9. https://doi.org/10.4103/JETS.JETS_21_17.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Huang Y, Wang S, Liu Y, et al. A preliminary study on the ultrasonic manifestations of peripulmonary lesions of non-critical novel coronavirus pneumonia (COVID-19). SSRN. 2020; https://doi.org/10.2139/ssrn.3544750.

  15. Volpicelli G, Gargani L. Sonographic signs and patterns of COVID-19 pneumonia. Ultrasound J. 2020;12:22. https://doi.org/10.1186/s13089-020-00171-w.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Hansell DM, Bankier AA, MacMahon H, McLoud TC, Müller NL, Remy J. Fleischner society: glossary of terms for thoracic imaging. Radiology. 2008;246:697–722. https://doi.org/10.1148/radiol.2462070712.

    Article  PubMed  Google Scholar 

  17. Fang Y, Zhang H, Xie J, Lin M, Ying L, Pang P, et al. Sensitivity of chest CT for COVID-19: comparison to RT-PCR. Radiology. 2020;2:200432. https://doi.org/10.1148/radiol.20202004.32.

    Article  Google Scholar 

  18. Ai T, Yang Z, Hou H, Zhan C, Chen C, Lv W, et al. Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19) in China: a report of 1014 cases. Radiology. 2020; https://doi.org/10.1148/radiol.2020200642.

  19. Pan F, Ye T, Sun P, Gui S, Liang B, Li L, et al. Time course of lung changes on chest CT during recovery from 2019 novel coronavirus (COVID-19) Pneumonia. Radiology. 2020; https://doi.org/10.1148/radiol.2020200370.

  20. Song F, Shi N, Shan F, Zhang Z, et al. Emerging 2019 novel coronavirus (2019-nCoV) pneumonia. Radiology. 2020;295(1):210–7.

    Article  PubMed  Google Scholar 

  21. Zhu T, Wang Y, Zhou S, Zhang N, Xia L. A comparative study of chest computed tomography features in young and older adults with corona virus disease (COVID-19). J Thorac Imaging. 2020;35:W97. https://doi.org/10.1097/RTI.0000000000000513.

    Article  PubMed  PubMed Central  Google Scholar 

  22. Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497–506.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  23. Chung M, Bernheim A, Mei X, et al. CT imaging features of 2019 novel coronavirus (2019-nCoV). Radiology. 2020;295(1):202–7.

    Article  PubMed  Google Scholar 

  24. Shi H, Han X, Jiang N, et al. Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study. Lancet Infect Dis. 2020;20:425–34. https://doi.org/10.1016/S1473-3099(20)30086-4.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  25. Liu KC, Xu P, Lv W-F, et al. CT manifestations of coronavirus disease-2019: a retrospective analysis of 73 cases by disease severity. Eur J Radiol. 2020;126:108941. https://doi.org/10.1016/j.ejrad.2020.108941.

    Article  PubMed  PubMed Central  Google Scholar 

  26. Wang K, Kang S, Tian R, Zhang X, Zhang X, Wang Y. Imaging manifestations and diagnostic value of chest CT of coronavirus disease 2019 (COVID-19) in the Xiaogan area. Clin Radiol. 2020;75:341–7. https://doi.org/10.1016/j.crad.2020.03.004.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  27. Guan CS, Lv ZB, Yan S, et al. Imaging features of coronavirus disease 2019 (COVID-19): evaluation on thin-section CT. Acad Radiol. 2020;27:609–13. https://doi.org/10.1016/j.acra.2020.03.002.

    Article  PubMed  PubMed Central  Google Scholar 

  28. Ojha V, Mani A, Pandey NN, Kumar SS, Kumar S. CT in coronavirus disease 2019 (COVID-19): a systematic review of chest CT findings in 4410 adult patients. Eur Radiol. 2020; https://doi.org/10.1007/s00330-020-06975-7.

  29. Zhao W, Zhong Z, Xie X, et al. Relation between chest CT findings and clinical conditions of coronavirus disease (COVID-19) pneumonia: a multicenter study. Am J Roentgenol. 2020;214:1072–7. https://doi.org/10.2214/AJR.20.22976.

    Article  Google Scholar 

  30. Sun P, Qie S, Liu Z, Ren J, Jianing XJ. Clinical characteristics of 50466 patients with 2019-nCoV infection. medRxiv 2020;2020.02.18.20024539.

    Google Scholar 

  31. Qian K, Deng Y, Tai Y, Peng J, Peng H, Jiang L. Clinical characteristics of 2019 novel infected coronavirus pneumonia: a systemic review and meta-analysis. medRxiv 2020; 2020.02.14.20021535.

    Google Scholar 

  32. Salehi S, Abedi A, Balakrishnan S, Gholamrezanezhad A. Coronavirus disease 2019 (COVID-19): a systematic review of imaging findings in 919 patients. Am J Roentgenol. 2020;215:87–93. https://doi.org/10.2214/AJR.20.23034.

    Article  Google Scholar 

  33. Zompatori M, Ciccarese F, Fasano L. Overview of current lung imaging in acute respiratory distress syndrome. Eur Respir Rev. 2014;23:519–30. https://doi.org/10.1183/09059180.00001314.

    Article  PubMed  Google Scholar 

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Acknowledgments

The authors declare no conflict of interest.

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Authors and Affiliations

  1. Department of Radiology, Azienda Ospedali dei Colli, Monaldi Hospital, Naples, Italy

    Tullio Valente & Federica Romano

Authors
  1. Tullio Valente
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  2. Federica Romano
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Editors and Affiliations

  1. Geriatric and Intensive Geriatric Cares, San Giuseppe Moscati Hospital, Avellino, Italy

    Nicola Vargas

  2. International NIV School and Fellow Program, Intensive Care Unit, Hospital Morales Meseguer, Murcia, Spain

    Antonio M. Esquinas

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Valente, T., Romano, F. (2020). The Diagnosis of COVID ARF in Elderly: The Radiological Findings in Elderly. In: Vargas, N., Esquinas, A.M. (eds) Covid-19 Airway Management and Ventilation Strategy for Critically Ill Older Patients. Springer, Cham. https://doi.org/10.1007/978-3-030-55621-1_6

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  • DOI: https://doi.org/10.1007/978-3-030-55621-1_6

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-55620-4

  • Online ISBN: 978-3-030-55621-1

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