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COVID-19 Classification Using CT Scans with Convolutional Neural Networks

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Computerized Systems for Diagnosis and Treatment of COVID-19

Abstract

Even with more than 12 billion vaccine doses administered globally, the Covid-19 pandemic has caused several global economic, social, environmental, and healthcare impacts. Computer Aided Diagnostic (CAD) systems can serve as a complementary method to aid doctors in identifying regions of interest in images and help detect diseases. In addition, these systems can help doctors analyze the status of the disease and check for their progress or regression. To analyze the viability of using CNNs for differentiating Covid-19 CT positive images from Covid-19 CT negative images, we used a dataset collected by Union Hospital (HUST-UH) and Liyuan Hospital (HUST-LH) and made available at the Kaggle platform. The main objective of this chapter is to present results from applying two state-of-the-art CNNs on a Covid-19 CT Scan images database to evaluate the possibility of differentiating images with imaging features associated with Covid-19 pneumonia from images with imaging features irrelevant to Covid-19 pneumonia. Two pre-trained neural networks, ResNet50 and MobileNet, were fine-tuned for the datasets under analysis. Both CNNs obtained promising results, with the ResNet50 network achieving a Precision of 0.97, a Recall of 0.96, an F1-score of 0.96, and 39 false negatives. The MobileNet classifier obtained a Precision of 0.94, a Recall of 0.94, an F1-score of 0.94, and a total of 20 false negatives.

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References

  1. Ct scans for covid-19 classification — kaggle. https://www.kaggle.com/datasets/azaemon/preprocessed-ct-scans-for-covid19. (Accessed 13 Nov 2022)

  2. Chassagnon G, Vakalopoulou M, Régent A, Sahasrabudhe M, Marini R, Hoang-Thi T-N, Dinh-Xuan A-T, Dunogué B, Mouthon L, Paragios N, Revel M-P (2021) Elastic registration-driven deep learning for longitudinal assessment of systemic sclerosis interstitial lung disease at ct. Radiology 298(1):189–198. PMID: 33078999

    Google Scholar 

  3. Gardner L, Dong E, Du H (2020) An interactive web-based dashboard to track covid-19 in real time. Lancet Inf Dis 20(5):533–534

    Article  Google Scholar 

  4. Falconí LG, Pérez M, Aguilar WG (20198) Transfer learning in breast mammogram abnormalities classification with mobilenet and nasnet. In: 2019 international conference on systems, signals and image processing (IWSSIP), pp 109–114

    Google Scholar 

  5. Gildenblat J, and Contributors (2021) Pytorch library for cam methods. https://github.com/jacobgil/pytorch-grad-cam

  6. He K, Zhang X, Ren S, Sun J (2016) Deep residual learning for image recognition. In: 2016 IEEE conference on computer vision and pattern recognition (CVPR), pp 770–778

    Google Scholar 

  7. Ho TT, Kim T, Kim WJ, Lee CH, Chae KJ, Bak SH, Kwon SO, Jin GY, Park EK, Choi S (2021) A 3d-cnn model with ct-based parametric response mapping for classifying copd subjects. Sci Rep 11(1):34

    Article  Google Scholar 

  8. Howard AG, Zhu M, Chen B, Kalenichenko D, Wang W, Weyand T, Andreetto M, Adam H (2017) Mobilenets: efficient convolutional neural networks for mobile vision applications. CoRR arXiv:abs/1704.04861

  9. Hryniewska W, Bombiński P, Szatkowski P, Tomaszewska P, Przelaskowski A, Biecek P (2021) Checklist for responsible deep learning modeling of medical images based on covid-19 detection studies. Pattern Recognit 118:108035

    Article  Google Scholar 

  10. Huang SC, Kothari T, Banerjee I, Chute C, Ball RL, Borus N, Huang A, Patel BN, Rajpurkar P, Irvin J, Dunnmon J, Bledsoe J, Shpanskaya K, Dhaliwal A, Zamanian R, Ng AY, Lungren MP (2020) Penet—a scalable deep-learning model for automated diagnosis of pulmonary embolism using volumetric ct imaging. npj Digit Med 3(1):61

    Google Scholar 

  11. Ko H, Chung H, Kang WS, Kim KW, Shin Y, Kang SJ, Lee JH, Kim YJ, Kim NY, Jung H, Lee J et al (2020) Covid-19 pneumonia diagnosis using a simple 2d deep learning framework with a single chest ct image: model development and validation. J Med Internet Res 22(6):e19569

    Article  Google Scholar 

  12. Li X, Tan W, Liu P, Zhou Q, Yang J (2021) Classification of covid-19 chest ct images based on ensemble deep learning. J Healthcare Eng 2021

    Google Scholar 

  13. Liu F, Tang J, Ma J, Wang C, Ha Q, Yizhou Yu, Zhou Z (2021) The application of artificial intelligence to chest medical image analysis. Intell Med 1(3):104–117

    Article  Google Scholar 

  14. Mattioli AV, Ballerini Puviani M, Nasi M, Farinetti A (2020) Covid-19 pandemic: the effects of quarantine on cardiovascular risk. Europ J Clin Nutrition 74(6):852–855

    Article  Google Scholar 

  15. Molnar C (2022) Interpretable machine learning, 2 edn

    Google Scholar 

  16. Ning W, Lei S, Yang J, Cao Y, Jiang P, Yang Q, Zhang J, Wang X, Chen F, Geng Z, Xiong L, Hongmei Z, Yaping G, Yulan Z, Heshui S, Wang L, Yu X, Wang Z (2020) Open resource of clinical data from patients with pneumonia for the prediction of covid-19 outcomes via deep learning. Nature Biomed Eng 4(12):1197–1207

    Article  Google Scholar 

  17. Özdemir Ö, Sönmez EB (2022) Attention mechanism and mixup data augmentation for classification of covid-19 computed tomography images. J King Saud Univers-Comput Inf Sci 34(8):6199–6207

    Google Scholar 

  18. Pathak Y, Shukla PK, Tiwari A, Stalin S, Singh S, Shukla PK (2022) Deep transfer learning based classification model for covid-19 disease. IRBM 43(2):87–92

    Article  Google Scholar 

  19. Polsinelli M, Cinque L, Placidi G (2020) A light cnn for detecting covid-19 from ct scans of the chest. Pattern Recogn Lett 140:95–100

    Article  Google Scholar 

  20. Rume T, Didar-Ul Islam SM (2020) Environmental effects of covid-19 pandemic and potential strategies of sustainability. Heliyon 6(9):e04965

    Article  Google Scholar 

  21. Salehi S, Abedi A, Balakrishnan S, Gholamrezanezhad A (2020) Coronavirus disease 2019 (covid-19): a systematic review of imaging findings in 919 patients. Am J Roentgenol 215(1):87–93. PMID: 32174129

    Google Scholar 

  22. Selvaraju RR, Cogswell M, Das A, Vedantam R, Parikh D, Batra D (2017) Grad-cam: Visual explanations from deep networks via gradient-based localization. In: Proceedings of the IEEE international conference on computer vision, pp 618–626

    Google Scholar 

  23. Shah V, Keniya R, Shridharani A, Punjabi M, Shah J, Mehendale N (2021) Diagnosis of covid-19 using ct scan images and deep learning techniques. Emerg Radiol 28(3):497–505

    Article  Google Scholar 

  24. Soares E, Angelov P, Biaso S, Froes MH, Abe DK (2020) Sars-cov-2 ct-scan dataset: a large dataset of real patients ct scans for sars-cov-2 identification. medRxiv

    Google Scholar 

  25. Valente IRS, Cortez PC, Neto EC, Soares JM, de Albuquerque VHC, Tavares JMRS (2016) Automatic 3d pulmonary nodule detection in ct images: a survey. Comput Methods Programs Biomed 124:91–107

    Article  Google Scholar 

  26. Wang Y, Mei X, Liu C, Deyer T, Zeng J, Xia C, Schefflein J, Jia L, Yu H, Jiang F, Yang C, Zhou P, Chang H, Robson P, Doshi A, Mendelson D, Zhu H, Powell C, Yang Y, Li W (2019) A generalized deep learning approach for evaluating secondary pulmonary tuberculosis on chest computed tomography. SSRN Electron J 01

    Google Scholar 

  27. Wang Z, Liu Q, Dou Q (2020) Contrastive cross-site learning with redesigned net for covid-19 ct classification. IEEE J Biomed Health Inform 24(10):2806–2813

    Article  Google Scholar 

  28. Wu B, Zhou Z, Wang J, Wang Y (2018) Joint learning for pulmonary nodule segmentation, attributes and malignancy prediction. In: 2018 IEEE 15th international symposium on biomedical imaging (ISBI 2018), pp 1109–1113

    Google Scholar 

  29. Xiong L, Zhong S, Li Y, Dai S, Bi L, Bo H, Zhang H, Zhimin M, Zeng S, Qi W et al (2020) Data-driven fuzzy multiple criteria decision making and its potential applications. Math Probl Eng 1(2):3

    Google Scholar 

  30. Yang X, He X, Zhao J, Zhang Y, Zhang S, Xie P (2020) Covid-ct-dataset: a ct scan dataset about covid-19

    Google Scholar 

  31. Zhang K, Liu X, Shen J, Li Z, Sang Y, Wu X, Zha Y, Liang W, Wang C, Wang K, Ye L, Gao M, Zhou Z, Li L, Wang J, Yang Z, Cai H, Xu J, Yang L, Cai W, Xu W, Wu S, Zhang W, Jiang S, Zheng L, Zhang X, Wang L, Lu L, Li J, Yin H, Wang W, Li O, Zhang C, Liang L, Wu T, Deng R, Wei K, Zhou Y, Chen T, Yiu-Nam Lau J, Fok M, He J, Lin T, Li W, Wang G (2020) Clinically applicable ai system for accurate diagnosis, quantitative measurements, and prognosis of covid-19 pneumonia using computed tomography. Cell 181(6):1423–1433.e11. 32416069[pmid]

    Google Scholar 

  32. Zhao W, Zhong Z, Xie X, Qizhi Yu, Liu J (2020) Relation between chest ct findings and clinical conditions of coronavirus disease (covid-19) pneumonia: a multicenter study. Am J Roentgenol 214(5):1072–1077. PMID: 32125873

    Google Scholar 

  33. Zhou T, Huiling L, Yang Z, Qiu S, Huo B, Dong Y (2021) The ensemble deep learning model for novel covid-19 on ct images. Appl Soft Comput 98:106885

    Article  Google Scholar 

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Correspondence to Jao Alexandre Lobo Marques .

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Motta, P.C., Cesar Cortez, P., Lobo Marques, J.A. (2023). COVID-19 Classification Using CT Scans with Convolutional Neural Networks. In: Lobo Marques, J.A., Fong, S.J. (eds) Computerized Systems for Diagnosis and Treatment of COVID-19. Springer, Cham. https://doi.org/10.1007/978-3-031-30788-1_7

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