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Therapeutic Angiogenesis: Translational and Clinical Experience

  • Living reference work entry
  • First Online:
Vascularization for Tissue Engineering and Regenerative Medicine

Part of the book series: Reference Series in Biomedical Engineering ((TIENRE))

  • 66 Accesses

Abstract

Therapeutic angiogenesis aims to target major public health issues, such as coronary artery disease and peripheral artery disease. Angiogenesis is often induced by gene therapy-derived transgene overexpression. Myriad of preclinical studies have been published during the last three decades, and over two thousand clinical trials have been concluded. Despite of the great enthusiasm on the research field, evolution to clinical applications has been slow. This chapter will discuss the accomplishments and challenges encountered on the path from bench to bedside.

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  1. A.I. Virtanen Institute, University of Eastern Finland, Kuopio, Finland

    Henna Korpela, Jaakko Lampela, Jussi Nurro, Juho Pajula & Seppo Ylä-Herttuala

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  1. AUVA Research Center, Ludwig Boltzmann Inst. Exp. a. Clinical AUVA Research Center, Wien, Vatican City State

    Wolfgang Holnthoner

  2. Department of Biomedicine, University Hospital Basel Department of Biomedicine, Basel, Switzerland

    Andrea Banfi

  3. Institute for Pathology, Johannes Gutenberg University Institute for Pathology, Mainz, Germany

    James Kirkpatrick

  4. LBI für experimentelle und klinisch, Wien, Austria

    Heinz Redl

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Korpela, H., Lampela, J., Nurro, J., Pajula, J., Ylä-Herttuala, S. (2021). Therapeutic Angiogenesis: Translational and Clinical Experience. In: Holnthoner, W., Banfi, A., Kirkpatrick, J., Redl, H. (eds) Vascularization for Tissue Engineering and Regenerative Medicine. Reference Series in Biomedical Engineering(). Springer, Cham. https://doi.org/10.1007/978-3-319-21056-8_23-1

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  • DOI: https://doi.org/10.1007/978-3-319-21056-8_23-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-21056-8

  • Online ISBN: 978-3-319-21056-8

  • eBook Packages: Springer Reference EngineeringReference Module Computer Science and Engineering

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