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Phytolacca americana L. and P. acinosa Roxb.

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Chinese Drugs of Plant Origin

Abstract

Shanglu, Radix Phytolaccae, is the dry root of Phytolacca acinosa Roxb. or P. americana L. (Phytolaccaceae) collected in the spring and fall. This officially in the Chinese Pharmacopoeia listed herbal medicine is toxic and to be used for treatment of edema or treatment of abscess by external administration.

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References

  1. Ahmed ZF, Zufall CJ, Jenkins GL (1949) A contribution to the chemistry and toxicology of the root of Phytolacca americana. J Am Pharm Assoc 38:443–448

    CAS  Google Scholar 

  2. Stout GH, Malofsky BM, Stout VF (1964) Phytolaccagenin: a light atom X-ray structure proof using chemical information. J Am Chem Soc 86:957–958

    Article  CAS  Google Scholar 

  3. Woo WS, Kang SS, Wagner H, Seligmann O, Chari VM (1978) Triterpenoid saponins from the roots of Phytolacca americana. Planta Med 34:87–92

    Article  CAS  Google Scholar 

  4. Woo WS, Kang SS (1976) Phytolaccoside B: triterpene glycoside from Phytolacca americana. Phytochemistry 15:1315–1317

    Article  CAS  Google Scholar 

  5. Suga Y, Maruyama Y, Kawanishi S, Shoji J (1978) Studies on the constituents of phytolaccaceous plants. I. On the structures of phytolaccasaponin B, E and G from the roots of Phytolacca americana L. Chem Pharm Bull (Tokyo) 26:520–525

    CAS  Google Scholar 

  6. Kang SS, Woo WS (1987) Two new saponins from Phytolacca americana. Planta Med 53:338–340

    Article  PubMed  CAS  Google Scholar 

  7. Woo WS, Kang SS (1977) The structure of phytolaccoside G. Yakhak Hoe Chi 21:159–162 (CA 88:191324h)

    Google Scholar 

  8. Kang SS, Woo WS (1980) Triterpenes from the berries of Phytolacca americana. J Nat Prod 43:510–513

    Article  CAS  Google Scholar 

  9. Burke DE, Le Quesne PW (1971) 3-Acetyloleanolic acid from Phytolacca americana seeds. Phytochemistry 10:3319–3320

    Article  CAS  Google Scholar 

  10. Woo WS, Wagner H (1977) 3-Acetylaleuritolic acid from the seeds of Phytolacca americana. Phytochemistry 16:1845–1846

    Article  CAS  Google Scholar 

  11. Woo WS (1974) Steroids and pentacyclic triterpenoids from Phytolacca americana. Phytochemistry 13:2887–2889

    Article  CAS  Google Scholar 

  12. Itoh T, Uetsuki T, Tamura T, Matsumoto T (1980) Characterization of triterpene alcohols of seed oils from some species of Theaceae, Phytolaccaceae and Sapotaceae. Lipids 15:407–411

    Article  CAS  Google Scholar 

  13. Woo WS, Kang SS, Wagner H, Chari VM (1978) The structure of americanin, a new neolignan from Phytolacca americana. Tetrahedron Lett 3239–3242

    Google Scholar 

  14. Lin LJ, Meksuriyen D, Cordell GA, Woo WS, Lee CK (1987) The structure of americanin A. Saengyak Hakhoechi 18:94–98 (CA 107:242496m)

    CAS  Google Scholar 

  15. Woo WS, Kang SS, Seligmann O, Chari VM, Wagner H (1980) The structure of new lignans from the seeds of Phytolacca americana. Tetrahedron Lett 21:4255–4258

    Article  CAS  Google Scholar 

  16. Hasegawa T, Fukuyama Y, Koshino K, Nakagawa K, Tori M, Asakawa Y (1987) Studies of isoamericanin A, a prostaglandin I2 inducer, isolated from the seeds of Phytolacca americana L. Chem Lett 329–332

    Google Scholar 

  17. Funayama S, Hikino H (1979) Hypotensive principles of Phytolacca roots. J Nat Prod 42:672–674

    Article  PubMed  CAS  Google Scholar 

  18. Irvin JD, Kelly T, Robertus JD (1980) Purification and properties of a second antiviral protein from Phytolacca americana which inactivates eukaryotic ribosomes. Arch Biochem Biophys 200:418–425

    Article  PubMed  CAS  Google Scholar 

  19. Houston LL, Ramakrishnan S, Hermodson MA (1983) Seasonal variations in different forms of pokeweed antiviral protein, a potent inactivator of ribosomes. J Biol Chem 258:9601–9604

    PubMed  CAS  Google Scholar 

  20. Barbieri L, Aron GM, Irvin JD, Stirpe F (1982) Purification and partial characterization of another form of the antiviral protein from the seeds of Phytolacca americana L. (pokeweed). Biochem J 203:55–59

    PubMed  CAS  Google Scholar 

  21. Wyatt SD, Shepherd RJ (1969) Isolation and characterization of a virus inhibitor from Phytolacca americana. Phytopathology 59:1787–1794

    PubMed  CAS  Google Scholar 

  22. Robertus JD, Monzingo AF, Irvin JD (1977) Preliminary X-ray diffraction studies on a antiviral protein. Biochem Biophys Res Commun 74:775–779

    Article  PubMed  CAS  Google Scholar 

  23. Ready MP, Brown DT, Robertus JD (1986) Extracellular localization of pokeweed antiviral protein. Proc Natl Acad Sci USA 83:5053–5056

    Article  PubMed  CAS  Google Scholar 

  24. Yi YH, Wang ZL (1984) Active principles of Phytolacca esculenta. I. Isolation and identification of the triterpene saponins. Chin Trad Herb Drugs 15:55–59

    CAS  Google Scholar 

  25. Wang ZL, Yi YH (1984) Studies on the active principles of the traditional Chinese drug “Shang Lu” (Phytolacca esculenta Van Houtte). II. Isolation and identification of esculentoside E and F. Acta Pharm Sin 19:825–829

    CAS  Google Scholar 

  26. Glombitza KW, Gielsdorf W, Eckhardt G, Koch ML (1975) Triterpenoid sapogenins from the fruits of Phytolacca acinosa. Planta Med 27:367–371

    Article  CAS  Google Scholar 

  27. Razdan TK, Harkar S, Kachroo V, Koul GL (1982) Phytolaccanol and epiacetylaleuritolic acid, two triterpenoids from Phytolacca acinosa. Phytochemistry 21:2339–2342

    Article  CAS  Google Scholar 

  28. Razdan TK, Harkar S, Kachroo V, Koul GL, Waight ES (1983) Triterpenoids from Phytolacca, three oleanane derivatives. Phytochemistry 22:1797–1800

    Article  CAS  Google Scholar 

  29. Harkar S, Razdan TK, Waight ES (1984) Further triterpenoids and carbon-13 NMR spectra of oleanane derivatives from Phytolacca acinosa. Phytochemistry 23:2893–2898

    Article  CAS  Google Scholar 

  30. Woo WS, Shin KH, Kang SS (1976) Constituents of Phytolacca species. I. Antiinflammatory saponins. Soul Taehakkyo Saengyak Yonguso Opjukjip 15:103–106 (CA 88:146072p)

    CAS  Google Scholar 

  31. Woo WS, Shin KH (1976) Antiinflammatory action of Phytolacca saponin. Soul Taehakkyo Saengyak Yonguso Opjukjip 15:90–96 (CA 88:69156g)

    CAS  Google Scholar 

  32. Liu FC, Ding GX, Li JX (1984) Effects of the total saponin from Phytolacca root on the incorporation 3H-thymidine into liver and spleen tissue. Chin Trad Herb Drugs 15:506–508

    CAS  Google Scholar 

  33. Ussery MA, Irvin JD, Hardesty B (1977) Inhibition of poliovirus replication by a plant antiviral peptide. Am NY Acad Sci 284:431–440

    Article  CAS  Google Scholar 

  34. Masuho Y, Kishida K, Hara T (1982) Targeting of the antiviral protein from Phytolacca americana with an antibody. Biochem Biophys Res Commun 105:462–469

    Article  PubMed  CAS  Google Scholar 

  35. Ramakrishnan S, Houston LL (1984) Inhibition of human acute lymphoblastic leukemia cells by immunotoxins: potentiation by chloroquine. Science 223:58–61

    Article  PubMed  CAS  Google Scholar 

  36. Ramakrishnan S, Houston LL (1984) Comparison of the selective cytotoxic effects of immunotoxins containing ricin A chain or pokeweed antiviral protein and anti-Thy 1.1 monoclonal antibodies. Cancer Res 44:201–208

    PubMed  CAS  Google Scholar 

  37. Bjorn MJ, Larrick J, Piatak M, Wilson KJ (1984) Characterization of translational inhibitors from Phytolacca americana. Amino-terminal sequence determination and antibody-inhibitor conjugates. Biochim Biophys Acta 790:154–163

    Article  PubMed  CAS  Google Scholar 

  38. Ramakrishnan S, Houston LL (1985) Immunological and biological stability of immunotoxins in vivo as studied by the clearance of disulfide-linked pokeweed antiviral protein-antibody conjugates from blood. Cancer Res 45:2031–2036

    PubMed  CAS  Google Scholar 

  39. Lambert JM, Senter PD, Yau-Young A, Blattler WA, Goldmacher VS (1985) Purified immunotoxins that are reactive with human lymphoid cells. Monoclonal antibodies conjugated to the ribosome-inactivating proteins gelonin and the pokeweed antiviral proteins. J Biol Chem 260:12035–12041

    PubMed  CAS  Google Scholar 

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© 1992 Springer-Verlag Berlin Heidelberg

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Tang, W., Eisenbrand, G. (1992). Phytolacca americana L. and P. acinosa Roxb.. In: Chinese Drugs of Plant Origin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73739-8_97

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  • DOI: https://doi.org/10.1007/978-3-642-73739-8_97

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-73741-1

  • Online ISBN: 978-3-642-73739-8

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