Abstract
Mutants devoid of phosphofructokinase can catabolize hexose phosphates via 6-phosphogluconate; their failure to use glucose is the result of insufficiency of internal PEP, with consequent impairment of glucose uptake.
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References
Stadtman, E. R., Advan. Enzymol., 28, 41 (1966).
Sapico, V., Hanson, T. E., Walter, R. W., and Anderson, R. L., J. Bact., 96, 51 (1968).
Morissey, A. T. E., and Fraenkel, D. G., Biochem. Biophys. Res. Commun., 32, 467 (1968).
Kundig, W., Ghosh, S., and Roseman, S., Proc. US Nat. Acad. Sci., 52, 1067 (1964).
Anderson, A., and Cooper, R. A., J. Gen. Microbiol. (in the press).
Taylor, A. L., and Trotter, Carol D., Bact. Rev., 31, 332 (1967).
Morissey, A. T. E., and Fraenkel, D. G., J. Bact., 100, 1108 (1969).
Winkler, H. H., Biochim. Biophys. Acta, 117, 231 (1966).
Kornberg, H. L., and Smith, J., Nature, 224, 1261 (1969).
Roseman, S., J. Gen. Physiol., 54, 138s (1969).
Ashworth, J. M., and Kornberg, H. L., Proc. Roy. Soc., B, 165, 179 (1966).
Cooper, R. A., and Kornberg, H. L., Proc. Roy. Soc., B, 168, 263 (1968).
Morgan, M. J., and Kornberg, H. L., FEBS Letters, 3, 53 (1969).
Fraenkel, D. G., J. Biol. Chem., 243, 6458 (1968).
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KORNBERG, H., SMITH, J. Role of Phosphofructokinase in the Utilization of Glucose by Escherichia coli. Nature 227, 44–46 (1970). https://doi.org/10.1038/227044a0
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DOI: https://doi.org/10.1038/227044a0
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