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Abstract

This article summarizes the motivation for, and the proceedings of, the first ISA-TAB workshop held December 6–8, 2007, at the EBI, Cambridge, UK. This exploratory workshop, organized by members of the Microarray Gene Expression Data (MGED) Society's Reporting Structure for Biological Investigations (RSBI) working group, brought together a group of developers of a range of collaborative systems to discuss the use of a common format to address the pressing need of reporting and communicating data and metadata from biological, biomedical, and environmental studies employing combinations of genomics, transcriptomics, proteomics, and metabolomics technologies along with more conventional methodologies. The expertise of the participants comprised database development, data management, and hands-on experience in the development of data communication standards. The workshop's outcomes are set to help formalize the proposed Investigation, Study, Assay (ISA)-TAB tab-delimited format for representing and communicating experimental metadata. This article is part of the special issue of OMICS on the activities of the Genomics Standards Consortium (GSC).

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cover image OMICS: A Journal of Integrative Biology
OMICS A Journal of Integrative Biology
Volume 12Issue Number 2June 2008
Pages: 143 - 149
PubMed: 18447634

History

Published online: 19 June 2008
Published in print: June 2008
Published ahead of print: 30 April 2008

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    Susanna-Assunta Sansone
    EMBL-EBI The European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.
    Philippe Rocca-Serra
    EMBL-EBI The European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.
    Marco Brandizi
    EMBL-EBI The European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.
    Alvis Brazma
    EMBL-EBI The European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.
    Dawn Field
    NERC Centre for Ecology and Hydrology, Mansfield Rd, Oxford, United Kingdom.
    Jennifer Fostel
    NIH, National Institute of Environmental Health Science (NIEHS), Research Triangle Park, North Carolina.
    Andrew G. Garrow
    Unilever, Safety and Environmental Assurance Centre, Colworth Park, Sharnbrook, Bedford, United Kingdom.
    Jack Gilbert
    Plymouth Marine Laboratory, Prospect Place, Plymouth, United Kingdom.
    Federico Goodsaid
    Office of Clinical Pharmacology, Office of Translational Science, Center for Drug Evaluation and Research (CDER) U.S. Food and Drug Administration (FDA), Silver Spring, Maryland.
    Nigel Hardy
    Department of Computer Science, Aberystwyth University, Ceredigion, Wales, United Kingdom.
    Phil Jones
    EMBL-EBI The European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.
    Allyson Lister
    CISBAN & School of Computing Science, Newcastle University, Newcastle upon Tyne, United Kingdom.
    Michael Miller
    Rosetta Biosoftware, Seattle, Washington.
    Norman Morrison
    NERC Centre for Ecology and Hydrology, Mansfield Rd, Oxford, United Kingdom.
    NERC Bioinformatics Center (NEBC), Centre for Ecology and Hydrology, Oxford, United Kingdom, and the University of Manchester, School of Computer Science, Manchester, United Kingdom.
    Tim Rayner
    EMBL-EBI The European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.
    Nataliya Sklyar
    EMBL-EBI The European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.
    Chris Taylor
    EMBL-EBI The European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.
    Weida Tong
    FDA's National Center for Toxicological Research (NCTR), Center for Toxicoinformatics, Jefferson, Arkansas.
    Guy Warner
    Unilever, Safety and Environmental Assurance Centre, Colworth Park, Sharnbrook, Bedford, United Kingdom.
    Stefan Wiemann
    German Cancer Research Center, Heidelberg, Germany.
    and Members of the RSBI Working Group

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